HCG - Pregnancy, Serum, Quantitative
Label Mnemonic: SPGPOC
Epic Lab Code: LAB1148
Downtime Form: A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery
Chemistry
6240 RCP
356-3527
Specimen(s):
Plasma
Collection Medium:
Plasma Separator Tube 4.5 mL
Minimum:
3 mL whole blood in light green top tube or TWO Microtainer® devices.
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around Time:
30 minutes (upon receipt in laboratory)
Reference Range:
Weeks of gestation Expected range mIU/mL 3 weeks 5 - 72 4 weeks 10 - 708 5 weeks 217 - 8,245 6 weeks 152 - 32,177 7 weeks 4,059 - 153,767 8 weeks 31,366 - 149,094 9 weeks 59,109 - 135,901 10 weeks 44,186 - 170,409 12 weeks 27,107 - 201,165 14 weeks 24,302 - 93,646 15 weeks 12,540 - 69,747 16 weeks 8,904 - 55,332 17 weeks 8,240 - 51,793 18 weeks 9,649 - 55,271 Non-pregnant females: < 3 mIU/mL Males: < 2 mIU/mL Healthy non-pregnant peri-menopausal and post-menopausal females may have HCG values up to 8 mIU/mL. Heterophile antibodies present in the serum of some patients may cause a false positive result in this assay.
Comments:
This assay may be significantly impacted by high-dose biotin (>5 mg dose) taken within previous 12 hours. High concentrations of biotin may lead to falsely decreased results. These concentrations may be found in patients taking over-the-counter supplements with biotin content much higher than nutritional requirements for biotin. Specimens should not be collected until at least 12 hours after the last dose.

This assay recognizes the intact HCG "holo-hormone" produced in pregnancy but may not recognize other forms of HCG (e.g., "nicked HCG") produced in other conditions such as tumors of the germs cells, ovaries, bladder, pancreas, stomach, lungs, and liver.

This test is also performed in the Iowa River Landing (IRL) clinical laboratory (for specimens drawn at that site).
Methodology:
Electrochemiluminescence Immunoassay
CPT Code:
84702
 
See Additional Information:
Biotin Interference with Immunoassays