Alkaline Phosphatase Isoenzyme
Label Mnemonic: | ALPI |
Epic code: | LAB2552 |
Downtime form: | Doctor/Provider Orders - Pathology Core and Specialty Care Nursery |
Commercial Mailout Laboratory
6240-8 RCP
356-8593
6240-8 RCP
356-8593
Specimen(s):
Serum
Specimen
Instructions:
Patient's age and sex are required.
Collection Medium:
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Red top tube 5 mL (Clot Activator) |
Minimum:
1 mL of serum divided into TWO tubes each containing 0.5 mL
Testing Schedule:
Alkaline Phosphatase: Monday through Sunday; Continuously
Alkaline Phosphatase Isoenzymes: Monday through Friday
Alkaline Phosphatase Isoenzymes: Monday through Friday
Turn Around
Time:
2 days upon receipt at reference laboratory
Reference Range:
ALKALINE PHOSPHATASE Males Females 4 years: 149-369 U/L 4 years: 169-372 U/L 5 years: 179-416 U/L 5 years: 162-355 U/L 6 years: 179-417 U/L 6 years: 169-370 U/L 7 years: 172-405 U/L 7 years: 183-402 U/L 8 years: 169-401 U/L 8 years: 199-440 U/L 9 years: 175-411 U/L 9 years: 212-468 U/L 10 years: 191-435 U/L 10 years: 215-476 U/L 11 years: 185-507 U/L 11 years: 178-526 U/L 12 years: 185-562 U/L 12 years: 133-485 U/L 13 years: 182-587 U/L 13 years: 120-449 U/L 14 years: 166-571 U/L 14 years: 153-362 U/L 15 years: 138-511 U/L 15 years: 75-274 U/L 16 years: 102-417 U/L 16 years: 61-264 U/L 17 years: 69-311 U/L 17-23 years: 52-144 U/L 18 years: 52-222 U/L 24-45 years: 37-98 U/L > or =19 years: 45-115 U/L 46-50 years: 39-100 U/L 51-55 years: 41-108 U/L 56-60 years: 46-118 U/L 61-65 years: 50-130 U/L > or =66 years: 55-142 U/L Reference values have not been established for patients that are <4 years of age. ALKALINE PHOSPHATASE ISOENZYMES Liver 1% Liver 1 0-6 years: 5.1-49.0% 0-6 years: 7.0-112.7 IU/L 7-9 years: 3.0-45.0% 7-9 years: 7.4-109.1 IU/L 10-13 years: 2.9-46.3% 10-13 years: 7.8-87.6 IU/L 14-15 years: 7.8-48.9% 14-15 years: 10.3-75.6 IU/L 16-18 years: 14.9-50.5% 16-18 years: 13.7-78.5 IU/L > or =19 years: 27.8-76.3% > or =19 years: 16.2-70.2 IU/L Liver 2% Liver 2 0-6 years: 2.9-13.7% 0-6 years: 3.0-41.5 IU/L 7-9 years: 3.7-12.5% 7-9 years: 4.0-35.6 IU/L 10-13 years: 2.9-22.3% 10-13 years: 3.3-37.8 IU/L 14-15 years: 2.2-19.8% 14-15 years: 2.2-32.1 IU/L 16-18 years: 1.9-12.5% 16-18 years: 1.4-19.7 IU/L > or =19 years: 0.0-8.0% > or =19 years: 0.0-5.8 IU/L Bone % Bone 0-6 years: 41.5-82.7% 0-6 years: 43.5-208.1 IU/L 7-9 years: 39.9-85.8% 7-9 years: 41.0-258.3 IU/L 10-13 years: 31.8-91.1% 10-13 years: 39.4-346.1 IU/L 14-15 years: 30.6-85.4% 14-15 years: 36.4-320.5 IU/L 16-18 years: 38.9-72.6% 16-18 years: 32.7-214.6 IU/L > or =19 years: 19.1-67.7% > or =19 years: 12.1-42.7 IU/L Intestine % Intestine 0-6 years: 0.0-18.4% 0-6 years: 0.0-37.7 IU/L 7-9 years: 0.0-18.3% 7-9 years: 0.0-45.6 IU/L 10-13 years: 0.0-11.8% 10-13 years: 0.0-40.0 IU/L 14-15 years: 0.0-8.2% 14-15 years: 0.0-26.4 IU/L 16-18 years: 0.0-8.7% 16-18 years: 0.0-12.7 IU/L > or =19 years: 0.0-20.6% > or =19 years: 0.0-11.0 IU/L Placental Not present
Comments:
Useful for: Diagnosis and treatment of liver, bone, intestinal, and parathyroid diseases Determining the tissue source of increased alkaline phosphatase (ALP) activity in serum Differentiating between liver and bone sources of elevated ALP
Test
Limitations:
Bone Specific Alkaline Phosphatase and 5'nucleotidase may be useful in
identifying disorders of bone and liver, respectively.
Methodology:
ALP: Photometric, p-Nitrophenol Phosphate
ALKE: Electrophoresis
ALKE: Electrophoresis
CPT Code:
84075, 84080