Alkaline Phosphatase
Label Mnemonic: ALP
Epic code: LAB112
Downtime form: A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery
Chemistry
6240 RCP
356-3527
Specimen(s):
Plasma
Collection Medium:
Plasma Separator Tube 4.5 mL
Alternate Collection Media:
Call laboratory for additional acceptable specimen collection containers.
Minimum:
3 mL whole blood in light green top tube or ONE Microtainer® for pediatric patients.
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around Time:
1 hour (upon receipt in laboratory)
Reference Range:
 
        AGE                   MALES         FEMALES
       0 - 14 days         83-248 U/L     83-248 U/L
 15 days - 12 months      122-469 U/L    122-469 U/L
       1 - 9 years        142-335 U/L    142-335 U/L
      10 - 12 years       129-417 U/L    129-417 U/L
      13 - 14 years       116-468 U/L     57-254 U/L
      15 - 16 years        82-331 U/L     50-117 U/L
      17 - 18 years        55-149 U/L     45-87 U/L
19+ years [unchanged]      40-129 U/L     35-104 U/L
Comments:
Pediatric reference ranges updated 5/23/2017 (see reference below).

This test is also performed in the Iowa River Landing (IRL) clinical laboratory (for specimens drawn at that site).
Test Limitations:
Criterion: Recovery within plus or minus 10% of initial values.

Icterus: No significant interference up to an I Index of 60 for 
conjugated bilirubin corresponding to approximately 60 mg/dL 
conjugated and unconjugated bilirubin.

Hemolysis: No significant interference up to an H index of 500 
(approximate hemoglobin concentration: 500 mg/dL).

Lipemia (Intralipid): No significant interference up to an L index of 
2000. There is poor correlation between turbidity and triglycerides 
concentration.

Reference
Estey MP, Cohen AH, Colantonio DA, et al. CLSI-based transference of 
the CALIPER database of pediatric reference intervals from Abbott to 
Beckman, Ortho, Roche and Siemens Clinical Chemistry Assays: Direct 
validation using reference samples from the CALIPER cohort. Clin 
Biochem 2013;46:1197-1219.
Methodology:
Colorimetric
CPT Code:
84075
 
See also:
Alkaline Phosphatase-Other, Body Fluid