Alkaline Phosphatase
Label Mnemonic: ALP
Epic Lab Code: LAB112
Downtime Form: A-1a General Laboratory Requisition
6240 RCP
Collection Medium:
Plasma Separator Tube 4.5 mL
Alternate Collection Media:
Call laboratory for additional acceptable specimen collection containers.
3 mL whole blood in light green top tube or ONE Microtainer® for pediatric patients.
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around Time:
1 hour (upon receipt in laboratory)
Reference Range:
        AGE                   MALES         FEMALES
       0 - 14 days         83-248 U/L     83-248 U/L
 15 days - 12 months      122-469 U/L    122-469 U/L
       1 - 9 years        142-335 U/L    142-335 U/L
      10 - 12 years       129-417 U/L    129-417 U/L
      13 - 14 years       116-468 U/L     57-254 U/L
      15 - 16 years        82-331 U/L     50-117 U/L
      17 - 18 years        55-149 U/L     45-87 U/L
19+ years [unchanged]      40-129 U/L     35-104 U/L
Pediatric reference ranges updated 5/23/2017 (see reference below).

This test is also performed in the Iowa River Landing (IRL) clinical laboratory (for specimens drawn at that site).
Test Limitations:
Criterion: Recovery within plus or minus 10% of initial values. Icterus: No significant interference up to an I Index of 60 for conjugated bilirubin corresponding to approximately 60 mg/dL conjugated and unconjugated bilirubin. Hemolysis: No significant interference up to an H index of 500 (approximate hemoglobin concentration: 500 mg/dL). Lipemia (Intralipid): No significant interference up to an L index of 2000. There is poor correlation between turbidity and triglycerides concentration. Reference Estey MP, Cohen AH, Colantonio DA, et al. CLSI-based transference of the CALIPER database of pediatric reference intervals from Abbott to Beckman, Ortho, Roche and Siemens Clinical Chemistry Assays: Direct validation using reference samples from the CALIPER cohort. Clin Biochem 2013;46:1197-1219.
CPT Code:
See also:
Alkaline Phosphatase-Other, Body Fluid