Phenobarbital Drug Level
Label Mnemonic: PHEB
Epic Lab Code: LAB30
Downtime Form: A-1a Therapeutic Drug Assay Requisition
Chemistry
6240 RCP
356-3527
Specimen(s):
Plasma
Collection Medium:
Plasma Separator Tube 4.5 mL
Alternate Collection Media:
Call laboratory for additional acceptable specimen collection containers.
Minimum:
3 mL; light green top tube or ONE Microtainer®.
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around Time:
1 hour (upon receipt in laboratory)
Reference Range:
Therapeutic range: 15-40 μg/mL
Toxic concentration > 60 μg/mL
Coma without reflexes may occur at concentrations > 100 μg/mL.
Test Limitations:
Icterus: No significant interference up to an I index of 60 (approximate bilirubin concentration: 60 mg/dL). Hemolysis: No significant interference up to an H index of 1000 (approximate hemoglobin concentration: 1000 mg/dL). Lipemia (Intralipid): No significant interference up to an L index of 600 (approximate triglyceride concentration: 1200 mg/dL). There is poor correlation between turbidity and triglycerides concentration. Rheumatoid factor: No significant interference up to a concentration of 200 IU/mL. Mephobarbital (greater than 100%) and amobarbital (greater than 20%) show significant cross-reactivity. As with any assay employing mouse antibodies, the possibility exists for interference by human anti-mouse antibodies (HAMA) in the sample, which could cause falsely elevated results.
Methodology:
Kinetic Interaction of Microparticles in Solution (KIMS)
CPT Code:
80345
 
See Additional Information:
Chemistry Critical Lab Values