Label Mnemonic: HGU
Epic Lab Code: LAB408
Downtime Form: A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery
Commercial Mail-out Laboratory
5231 RCP
Specimen Instructions:
Refrigerate during collection in plastic container. Studies indicate that refrigeration of urine alone, during and after collection, preserves specimens adequately, if tested within 14 days of collection.

Patient Prep: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non- essential over-the-counter medications (upon the advice of their physician). High concentrations of iodine may interfere with elemental testing. Abstinence from iodine-containing medications or contrast agents for at least 1 month prior to collecting specimens for elemental testing is recommended.
Collection Medium:
Urine - 24 hour/timed plastic urine container
Preferred Minimum: 8 mL aliquot from a well-mixed collection from 24 hour collection.

Absolute Minimum: 1 mL aliquot from a well-mixed collection from 24 hour collection.

Refrigerate during collection and submission.
Rejection Criteria:
Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media (may occur with MRI studies). Acid preserved urine. Specimens contaminated with blood or fecal material. Specimens transported in non-trace element free transport tube (with the exception of the original device).
Turn Around Time:
4 days upon receipt at reference laboratory
Reference Range:
COMPONENTS REFERENCE INTERVAL Mercury, Urine-per 24h 0.0-2.9 μg/L Mercury, Urine-per volume 0.0-1.9 μg/d Mercury, Urine-ratio to CRT 0.0-20.0 μg/gCRT Creatinine, Urine-per 24h mg/d Male Female 3-8 yrs: 140-700 3-8 yrs: 140-700 9-12 yrs: 300-1300 9-12 yrs: 300-1300 13-17 yrs: 500-2300 13-17 yrs: 400-1600 18-50 yrs: 1000-2500 18-50 yrs: 700-1600 51-80 yrs: 800-2100 51-80 yrs: 500-1400 81 yrs+: 600-2000 81 yrs+: 400-1300
Interpretive Data:
Urinary mercury levels predominantly reflect acute or chronic elemental or inorganic mercury exposure. Urine concentrations in unexposed individuals are typically less than 10 g/L. 24 hour urine concentrations of 30 to 100 g/L may be associated with subclinical neuropsychiatric symptoms and tremor while concentrations greater than 100 g/L can be associated with overt neuropsychiatric disturbances and tremors. Urine mercury levels may be useful in monitoring chelation therapy.
Record total volume and collection time interval on transport tube and on test request form.

Stability: Mercury is volatile; concentration may reduce after seven days or more storage.
Quantitative Inductively Coupled Plasma-Mass Spectrometry
CPT Code: