|Downtime form:||A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery|
|Red top tube 5 mL (Clot Activator)|
Absolute Minimum: 0.2 mL serum from red top tube
Lymphocytic Choriomeningitis (LCM) Virus Antibody, IgG Less than 1:10 Negative - No significant level of LCM virus IgG antibody detected. Greater than or equal to 1:10 Positive - Presence of IgG antibody to LCM virus detected, suggestive of current or past infection. Lymphocytic Choriomeningitis (LCM) Virus Antibody, IgM Less than 1:10 Negative - No significant level of LCM virus IgM antibody detected. Greater than or equal to 1:10 Positive - Presence of IgM antibody to LCM virus detected, suggestive of current or past infection.
Lymphocytic choriomeningitis (LCM) is caused by an RNA virus now classified as an arenavirus. Rodents are the primarily reservoir. Clinically, infection usually presents as an acute influenza-like illness. Symptoms develop 5-10 days after exposure. Most patients develop fevers of 101-104 degrees F with chills and muscle rigidity. Other symptoms may include malaise, retro-orbital headache, photophobia, weakness, anorexia, nausea, and light-headedness. Some patients may experience sore throat. Symptoms may improve after five days to three weeks, but some suffer relapse with meningeal symptoms. The CF test is often used to screen aseptic meningitis specimens against a battery of antigens and a CF antigen is often appropriately included in this battery.