Aminolevulinic Acid
Label Mnemonic: ALA
Epic Lab Code: LAB2579
Downtime Form: A-1a Miscellaneous Request
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
Urine (24 hour or random) More information
Specimen Instructions:
Refrigerate during 24 hr collection.

Refrain from alcohol consumption 24 hours prior to collection.
Collection Medium:
Urine - 24 hour/timed dark plastic urine container
Minimum:
Collect 4 mL from a 24 hr or random urine.
Rejection Criteria:
Body fluids other than urine.
Turn Around Time:
1-4 days upon receipt at reference laboratory
Reference Range:
Aminolevulinic Acid, Urine 0-35 μmol/L Aminolevulinic Acid, Urine 0-60 μmol/d Creatinine, 24-Hour Urine Male 3-8 years: 140-700 mg/d 9-12 years: 300-1300 mg/d 13-17 years: 500-2300 mg/d 18-50 years: 1000-2500 mg/d 51-80 years: 800-2100 mg/d 81 years and older: 600-2000 mg/d Female 3-8 years: 140-700 mg/d 9-12 years: 300-1300 mg/d 13-17 years: 400-1600 mg/d 18-50 years: 700-1600 mg/d 51-80 years: 500-1400 mg/d 81 years and older: 400-1300 mg/d
Comments:
Increased ALA concentration is associated with exposure to alcohol, lead, and a variety of other agents. Massive elevation of ALA occurs in the acute porphyrias and hereditary tyrosinemia.

Specimen preservation with acid or base is discouraged and may cause assay interference. When collecting urine for additional tests that require acid or base preservation, the ALA aliquot should be removed prior to the addition of the acid or base.
Methodology:
Quantitative Ion Exchange Chromatography/Spectrophotometry
CPT Code:
82135