Islet Cell Antibody, IgG
Label Mnemonic: ISLET
Epic Lab Code: LAB3446
Downtime Form: A-1a Miscellaneous Request
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
Serum
Collection Medium:
Red top tube 5 mL (Clot Activator)
Minimum:
Recommended Minimum: 1 mL serum from red top tube
Absolute Minimum: 0.15 mL serum from red top tube
Rejection Criteria:
Plasma. Contaminated, hemolyzed, or severely lipemic specimens.
Turn Around Time:
3 days upon receipt at reference laboratory
Reference Range:
< 1:4 No antibody detected
Interpretive Data:
Islet cell antibodies (ICAs) are associated with type 1 diabetes (T1D), an autoimmune endocrine disorder. These antibodies may be present in individuals years before the onset of clinical symptoms. To calculate Juvenile Diabetes Foundation (JDF) units: multiply the titer x 5 (1:8 8 x 5 = 40 JDF Units).
Test Limitations:
Islet cell antibodies have been associated with "autoimmune" endocrine disorders and insulin-dependent diabetes. This disorder is characterized by the presence of antibodies in patients that may be detected years before the onset of the clinical symptoms. To calculate Juvenile Diabetes Foundation (JDF) units: Multiple the titer x 5. EXAMPLE: 1:8 8 x 5 = 40 JDF Units
Methodology:
Semi-Quantitative Indirect Fluorescent Antibody
CPT Code:
86341