IgG Subclasses
Label Mnemonic: IGGSUB
Epic Lab Code: LAB3409
Downtime Form: A-1a Miscellaneous Request
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
Serum or Plasma
Collection Medium:
Red top tube 5 mL (Clot Activator)
Alternate Collection Media:
Light Green top tube (Lithium Heparin) or Green top tube 4 mL (Na Heparin)
Minimum:
Preferred minimum: 2.0 mL serum
Absolute minimum: 0.45 mL serum
Turn Around Time:
3 days upon receipt at reference laboratory
Reference Range:
Immunoglobulin G Subclass 1: Immunoglobulin G Subclass 2: Cord blood: 435-1084 mg/dL Cord blood: 143-453 mg/dL 0-2 months: 218-498 mg/dL 0-2 months: 40-167 mg/dL 3-5 months: 143-394 mg/dL 3-5 months: 23-147 mg/dL 6-8 months: 190-388 mg/dL 6-8 months: 37-60 mg/dL 9-23 months: 288-880 mg/dL 9-23 months: 30-327 mg/dL 2 years: 170-950 mg/dL 2 years: 22-440 mg/dL 3-4 years: 290-1065 mg/dL 3-4 years: 28-315 mg/dL 5-6 years: 330-1065 mg/dL 5-6 years: 57-345 mg/dL 7-8 years: 225-1100 mg/dL 7-8 years: 42-375 mg/dL 9-10 years: 390-1235 mg/dL 9-10 years: 61-430 mg/dL 11-12 years: 380-1420 mg/dL 11-12 years: 73-455 mg/dL 13-14 years: 165-1440 mg/dL 13-14 years: 71-460 mg/dL 15 years & over: 240-1118 mg/dL 15 years & over: 124-549 mg/dL Immunoglobulin G Subclass 3: Immunoglobulin G Subclass 4: Cord blood: 27-146 mg/dL Cord blood: 1-47 mg/dL 0-2 months: 4-23 mg/dL 0-2 months: 1-33 mg/dL 3-5 months: 4-70 mg/dL 3-5 months: 1-14 mg/dL 6-8 months: 12-62 mg/dL 6-8 months: 1-16 mg/dL 9-23 months: 13-82 mg/dL 9-23 months: 1-65 mg/dL 2 years: 4-69 mg/dL 2 years: 0-120 mg/dL 3-4 years: 4-71 mg/dL 3-4 years: 0-90 mg/dL 5-6 years: 8-126 mg/dL 5-6 years: 2-116 mg/dL 7-8 years: 9-107 mg/dL 7-8 years: 0-138 mg/dL 9-10 years: 10-98 mg/dL 9-10 years: 1-95 mg/dL 11-12 years: 16-194 mg/dL 11-12 years: 1-153 mg/dL 13-14 years: 12-178 mg/dL 13-14 years: 2-143 mg/dL 15 years & over: 21-134 mg/dL 15 years & over: 1-123 mg/dL
Interpretive Data:
The total IgG (mg/dL) can be derived from the sum of the subclass IgG1, IgG2, IgG3, and IgG4 values. However, a confirmatory and more precise total IgG is available by the nephelometric method of quantitation for total IgG.
Comments:
Ordering Recommendation: Do not order for total IgG measurements. Secondary test in suspected immunoglobulin deficiency. Do not order before IgG, IgA, and IgM measurements are performed.
Methodology:
Quantitative Nephelometry
CPT Code:
82787(x4) IgG subclasses (1,2,3,4)