Non-allergic Adult:    0-100 IU/mL
Non-allergic Children: 10-20% of adult values

Neonates:  0.0-1.5 IU/mL
Infants in 1st year of life:  0-15 IU/mL
Children aged 1-5 years:  0-60 IU/mL
Children aged 6-9 years:  0-90 IU/mL
Children aged 10-15 years:  0-200 IU/mL

The assay is unaffected by icterus (bilirubin is less than 37 
mg/dL), hemolysis (Hb is less than 100 mg/dL), lipemia (triglycerides 
is less than 2200 mg/dL) and biotin is less than 100 ng/mL. 
(criterion: recovery within plus or minus 10% of initial value).

No interference was observed from rheumatoid factor up to 6000 U/mL 
(method comparison: Elecsys IgE and a comparison IgE test on 50 
samples).

No high dose hook effect at IgE concentrations of up to 50 000 IU/mL 
(120000 ng/mL).

In vitro tests were performed on 36 commonly used pharmaceuticals. No 
interference with the assay was found.

As with all tests containing monoclonal mouse antibodies, erroneous 
findings may be obtained from samples taken from patients who have 
been treated with monoclonal mouse antibodies or have received them 
for diagnostic purposes.

In rare cases interference due to extremely high titers of antibodies 
to ruthenium can occur.

IgE contains additives which minimize these effects.

Extremely high titers of antibodies to streptavidin can occur in 
isolated cases and cause interference.

For diagnostic purposes, the IgE findings should always be assessed in 
conjunction with the patient's medical history, clinical examination 
and other findings.