Tryptase, Total
Label Mnemonic: TRYP
Epic code: LAB4211
Downtime form: Doctor/Provider Orders - Pathology Core and Specialty Care Nursery
Commercial Mailout Laboratory
6240-8 RCP
356-8593
Specimen(s):
Serum
Collection Medium:
Red top tube 5 mL (Clot Activator)
Minimum:

Preferred Minimum: 0.5 mL serum
Absolute Minimum: 0.2 mL serum

Turn Around Time:

2 – 5 days upon receipt at reference laboratory.

Reference Range:

<11.5 ng/mL

Interpretive Data:

Transient tryptase concentrations greater than or equal to 11.5 ng/mL may be consistent with mast cell activation in the context of anaphylaxis or allergen challenge; measurement of tryptase in specimens obtained 1 to 6 hours and at least 24 hours after the episode may be useful in demonstrating a return to baseline concentrations.

 

Basal tryptase concentrations greater than or equal to 11.5 mg/mL may be consistent with cutaneous mastocytosis.

 

Basal tryptase concentrations greater than or equal to 20 ng/mL may be consistent with systemic mastocytosis.

Methodology:

Quantitative Fluorescent Enzyme Immunoassay

CPT Code:
83520