Histone Antibody, IgG
Label Mnemonic: HIST
Epic Lab Code: LAB3325
Downtime Form: A-1a Miscellaneous Request
Commercial Mail-out Laboratory
5231 RCP
356-8593
Specimen(s):
Serum
Collection Medium:
Red top tube 5 mL (Clot Activator)
Minimum:
Preferred Minimum: 0.5 mL serum
Absolute Minimum: 0.3 mL serum
Rejection Criteria:
Plasma or urine. Contaminated specimens. Grossly hemolyzed, lipemic, or icteric specimens.
Turn Around Time:
3 working days upon receipt at reference laboratory
Reference Range:
0.9 units or less Negative 1.0-1.5 units Weak Positive 1.6-2.5 units Moderate Positive 2.6 units or greater Strong Positive
Test Limitations:
Histone antibodies are present in 20-55% of idiopathic systemic lupus erythematosus (SLE) and 80-95% of drug-induced SLE. They occur in less than 20% of other types of connective tissues diseases.
Methodology:
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
CPT Code:
83516