Parvovirus B19 IgG/IgM

Label Mnemonic:	PARVO
Epic code:	LAB3806
Downtime form:	A-1a Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Commercial Mailout Laboratory
6240-8 RCP
356-8593

Specimen(s):

Serum

Specimen Instructions:

Mark specimens plainly as "acute" or "convalescent". Parallel testing is preferred and convalescent samples must be received within 30 days from receipt of acute samples.

Collection Medium:

Red top tube 5 mL (Clot Activator)

Minimum:

Preferred Minimum: 0.5 mL serum
Absolute Minimum: 0.3 mL serum

Rejection Criteria:

Contaminated, heat-inactivated, hemolyzed, lipemic, or icteric specimens.

Delivery Instructions:

Deliver to laboratory within 1 hour of collection.

Turn Around Time:

1-3 days upon receipt at reference laboratory

Reference Range:

Parvovirus B19 Antibody, IgG    0.90 IV or less: Negative - No
                                significant level of detectable 
                                Parvovirus B19 IgG antibody. 
                                -------------------------------------
                                0.91-1.09 IV: Equivocal - Repeat 
                                testing in 7-21 days may be helpful.
                                -------------------------------------
                                1.10 IV or greater: Positive - IgG 
                                antibody to Parvovirus B19 detected,
                                which may indicate a current or past 
                                infection. 

Parvovirus B 19 Antibody, IgM   0.90 IV or less: Negative - No 
                                significant level of detectable 
                                Parvovirus B19 IgM antibody. 
                                -------------------------------------
                                0.91-1.09 IV: Equivocal - Repeat 
                                testing in 7-21 days may be helpful.
                                -------------------------------------
                                1.10 IV or greater: Positive - IgM 
                                antibody to Parvovirus B19 detected,
                                which may indicate a current or recent
                                infection. However, low levels of IgM 
                                antibodies may occasionally persist
                                for more than 12 months post-
                                infection.

Methodology:

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

CPT Code:

86747(x2)

See also:
Parvovirus B19, PCR, Human, CSF, Amniotic Fluid, Synovial Fluid, Bone Marrow and Fresh Tissue (Snap Frozen)