Hemoglobin Electrophoresis, Pregnancy-Related Screening

Label Mnemonic:	HEPRS
Epic code:	LAB9531
Downtime form:	Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Hematology
6240 RCP
356-3527

Specimen(s):

Blood

Collection Medium:

Lavender top tube 3 mL (EDTA)

Minimum:

Full draw; 3.0 mL lavender top; (or fingerstick-purple top microtainer^®)

Testing Schedule:

This test is batched and run routinely on Fridays. If you need results STAT, call hematology resident (0800–1630, M-F) at 356-8628. All other times page the Pathology resident on-call at 3404.

Reference Range:

Hemoglobin A₂
  0-3.5%

Hemoglobin C
  0%

Hemoglobin F
  Birth-3 months: 50-80%
  3 months-1 Year: 6%
  After 1 year: 2% or less

Hemoglobin S
  0%

Comments:

This assay quantitates hemoglobin A, A2, C, F, and S levels using capillary electrophoresis and includes pathologist interpretation of hemoglobin electrophoresis pattern if abnormal. This would be appropriate order for initial workup of patient hemoglobin phenotype. For quantitation of fetal erythrocytes in maternal blood (e.g., workup of possible feto-maternal hemorrhage), "Fetal Erythrocyte Quantitation" (LAB292) would be appropriate order.

This test is appropriate for routine screening in pregnancy.

Methodology:

Capillary electrophoresis and Wright Stain

CPT Code:

83020