OtoSCOPE Panel
Label Mnemonic: OTOSCP
Epic code: LAB8064
Downtime form: Doctor/Provider Orders - Pathology Core and Specialty Care Nursery
Commercial Mailout Laboratory
6240-8 RCP
356-8593
Specimen(s):
Whole Blood, Saliva, or Buccal Swabs
Specimen Instructions:
Must include the following information:

  • Patient identifiers (full name, date of birth, sex and medical record number)
  • Pertinent history and clinical findings
  • Date of collection & sample type
  • Ordering physician

Samples may be refrigerated if delivery is delayed.
Collection Medium:
and
Pink top tube 6 mL (K2-EDTA) Pink top tube 6 mL (K2-EDTA)
Minimum:
Blood: 3-5cc EDTA Whole Blood- room temp
Saliva: DNA Genotek, ORAGene Discover, OGR-500
Buccal Swabs: DNA Genotek, OraCollect, OCD-100, at least 4 swabs
Delivery Instructions:
Samples accepted Monday-Friday.
Turn Around Time:
6 weeks
Reference Range:
None detected
Comments:
Please print, complete and submit the Hearing Loss Testing Requisition Form from the Molecular Otolaryngology & Renal Research Laboratories, to Specimen Control/Mailouts with the specimen and the Epic Requisition.

REASONS FOR TESTING: Genetic testing for hearing loss can provide important answers to many questions. By determining the cause of hearing loss, information can be given on recurrence risk for future children, prognosis (whether hearing loss will worsen over time), and best method of treatment (such as cochlear implants or hearing aids).

List of genes for current OtoSCOPE panel can be found on the MORL website: https://morl.lab.uiowa.edu/. Please contact MORL at 319-335-6623 or MORL@uiowa.edu for any questions or to speak with a member of the lab staff.
Methodology:
Next generation sequencing (NGS) with read depth analysis for copy number variant detection.
CPT Code:
81430, 81431