IDP

  • IDP is an gene Isoform Detection and Prediction tool
    from Second Generation Sequencing and PacBio sequencing.
    It offers very reliable gene isoform identification
    with high sensitivity
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Latest News: IDP 0.1.6 major update is released ... read more

How does IDP work?

IDP is a pure implementation of gene isoform/transcript identification by integrating long reads and short reads.

Relatively short gene isoforms can be detected directly if the full junction linkage can be covered by long reads.

Relatively long gene isoforms are predicted by selecting highly-expressed isoform candidates. Isoform candidates are constructed from long reads and junctions detected by short reads.

Abundance estimation is solved by Max A Posteriori of short read coverage. The priori is emprically approximated by direct-detection rate of transcripts w.r.t abundance and length.

IDP is geared towards any long reads and short reads, as long as they are generated from the same(at least similar) source. If you are having trouble running IDP, please let us know.