The following papers were generated by students from Graduate Course Free Radicals in Biology and Medicine (77:222) 2003.
Instructors
- Garry R. Buettner, Ph.D.
- Larry W. Oberley, Ph.D.
Please Note
In view of the possibility of human error or changes in our knowledge due to continued research, neither the authors nor The University of Iowa nor any other party who has been involved in the preparation or publication of this work warrants that the information contained herein is in every respect accurate or complete, and they are not responsible for any errors or omissions or for the results obtained from the use of such information. Readers are encouraged to confirmthe information contained herein with
other sources.
All material contained in these papers is copyright of the papers' author, or the owner of the source that the material was taken from. These works are not intended as threats to the ownership of said copyrights.
Paper 1
Author
| Title
| pdf |
Chauhan, Gaurav |
Phenoxyl
Radicals: Flavonoids
|
|
Fisher, Carolyn |
Lipid
Hydroperoxide (LOOH) of the Fatty Acid (FA) Nature
|
|
Gao, Zhen |
Hydroxyl
Radical and Its Detection Methods |
|
Hamsakutty, Harris |
Nitrogen
Dioxide Radical |
|
Hu, Sharon |
Hydroxyl
Radical |
|
Krager, Kim |
Superoxide
in Aprotic Solvents |
|
Li, Hualei |
Lipid Alkoxyl
Radicals |
|
Liu, Jingru |
Protein
Hydroperoxides ( POOH ) |
|
Menon, Sarita |
Nitrosoperoxocarboxylate |
|
Niu, Gang |
Hypochlorous
Acid |
|
Rodionov, Roman |
Chemistry
of peroxynitrite in biological systems |
|
Sarsour, Ehab |
Nitroxyl
(HNO/NO-) not Nitric Oxide (NO·) |
|
Slane, Benjamin |
CoQ Semiquinone
Radical |
|
Xiao, Ling |
Lipid Hydroperoxide
(LOOH) |
|
Yu, Lei |
Ozone, Bad
guy or good guy? |
|
Zheng, Xiaomei |
Tocopheroxyl
Radical |
|
Zimmerman, Matthew |
Sulfenic
Acids: An Overview |
|
Paper 2
Author |
Title
|
pdf
|
Chauhan, Gaurav |
Diethylenetriaminepentaacetic
acid (DTPA): A metal chelating agent |
|
Fisher, Carolyn |
Organoselenium
Compounds as Glutathione Peroxidase Mimics |
|
Gao, Zhen |
The
Anti-Oxidant Effects of Nitric Oxide |
|
Hamsakutty, Harris |
Cysteine |
|
Hu, Sharon |
Is Zinc
an Antioxidant ? |
|
Krager, Kim |
Bilirubin |
|
Li, Hualei |
Pyruvate,
a Sacrificial Antioxidant |
|
Liu, Jingru |
NADPH |
|
Menon, Sarita |
N-Acetyl-L-Cysteine |
|
Niu, Gang |
Vitamin
K |
|
Rodionov, Roman |
Urate
as an endogenous antioxidant |
|
Sarsour, Ehab |
Desferal® |
|
Slane, Benjamin |
Liopoic
Acid |
|
Xiao, Ling |
Desferrioxamine
(DFO) |
|
Yu, Lei |
Glutathione,
why we need it every day? |
|
Zheng, Xiaomei |
a-Tocopherol,
Lipid Antioxidant |
|
Zimmerman, Matthew |
Nitric
Oxide: An Antioxidant |
|
Paper 3
Author |
Title
|
pdf
|
Chauhan, Gaurav |
Glutathione
S-transferases: Family of enzymes
|
|
Fisher, Carolyn |
Melanin:
The Pigmented Truth
|
|
Gao, Zhen |
The Nuclear
Factor - kB |
|
Hamsakutty, Harris |
Heme
Oxygenase |
|
Hu, Sharon |
The Role
of p53 in the Redox Modulation in the DNA Binding |
|
Krager, Kim |
Heat
Shock Protein 90: The Shock Absorber
|
|
Li, Hualei |
OxyR,
a Redox-operated Switch |
|
Liu, Jingru |
Classic
Glutathione Peroxidase |
|
Menon, Sarita |
Peroxiredoxins |
|
Niu, Gang |
Myeloperoxidase |
|
Rodionov, Roman |
Endothelial
Nitric Oxide Synthase |
|
Sarsour, Ehab |
Hypoxia-inducible
factor 1 (HIF-1) |
|
Slane, Benjamin |
Thioredoxin:
a family conserved |
|
Xiao, Ling |
Thioredoxin
Reductase (TrxR) |
|
Yu, Lei |
NF- kB,
a redox regulated transcription factor |
|
Zheng, Xiaomei |
Extracellular
Superoxide Dismutase |
|
Zimmerman, Matthew |
NADPH
Oxidase |
|
Paper 4
Author |
Title
|
pdf
|
Chauhan, Gaurav |
Selenium:
The essential poison
|
|
Fisher, Carolyn |
Streptozocin
|
|
Gao, Zhen |
The
Toxicology of Carbon Tetrachloride |
|
Hamsakutty, Harris |
Adriamycin |
|
Hu, Sharon |
Paraquat
toxicity |
|
Krager, Kim |
Just
Sit Back and Relax with Sodium Nitroprusside |
|
Li, Hualei |
Dithiothreitol
(Cleland's Reagent) |
|
Liu, Jingru |
1,3-bis-Chloroethyl-1-Nitrosourea
(BCNU) |
|
Menon, Sarita |
Motexafin
Gadolinium |
|
Niu, Gang |
Bleomycin |
|
Rodionov, Roman |
Nitroglycerin |
|
Sarsour, Ehab |
Acetaminophen |
|
Slane, Benjamin |
Antimycin:
the big bad chain blocker |
|
Xiao, Ling |
Buthionine
Sulfoximine ( BSO ) |
|
Yu, Lei |
Ultraviolet
Radiation |
|
Zheng, Xiaomei |
Cigarette
Smoke |
|
Zimmerman, Matthew |
Streptozocin |
|
Paper 5
Author |
Title
|
pdf
|
Chauhan, Gaurav |
Sickle-cell
anemia
|
|
Fisher, Carolyn |
Parkinson's
Disease: A Review
|
|
Gao, Zhen |
Free
Radicals in the Rheumatoid Arthritis |
|
Hamsakutty, Harris |
Radiation-Induced
Fibrosis |
|
Hu, Sharon |
ALS |
|
Krager, Kim |
Alcoholism |
|
Li, Hualei |
Free Radicals
and Cataract |
|
Liu, Jingru |
Oxidative
Stress in Parkinson's disease |
|
Menon, Sarita |
Exploiting
redox regulation of cell cycle for novel breast cancer therapeutics |
|
Niu, Gang |
Free Radical
in Ischemia/reperfusion Injury |
|
Rodionov, Roman |
The roles
of free radicals in the pathogenesis of atherosclerosis |
|
Sarsour, Ehab |
Aging:
The role of MnSOD in life span extension through cell cycle and telomeres
maintenance |
|
Slane, Benjamin |
Leigh's
Syndrome |
|
Xiao, Ling |
Oxidative
Stress and Diabetes |
|
Yu, Lei |
Inflammation
and oxidative stress |
|
Zheng, Xiaomei |
Cancer |
|
Zimmerman, Matthew |
Central
Angiotensin II-Dependent Hypertension:
A Role for Reactive Oxygen Species
|
|
Appendix
Author |
Title
|
pdf
|
Buettner, Garry R. |
The Pecking Order of
Free Radicals and Antioxidants: Lipid Peroxidation, a-Tocopherol, and Ascorbate Arch Biochem Biophys 1993, 300: 535-543 |
|
Schafer, Freya Q. et al. |
Redox Environment of
the Cell as Viewed through the Redox State of the Glutathione Disulfide/Glutathione
Couple Free Radic Biol Med 2001, 30: 1191-1212 |
|
Hempel, Stephen L. et al. |
Dihydrofluorescein Diacetate
Is Superior for Detecting Intracellular Oxidants: Comparison with 2',7'-
Dichlorodihydrofluorescein Diacetate, 5(and 6)-Carboxy-2',7'-Dichlorodihydrofluorescein
Diacetate, and Dihydrorhodamine 123 Free Radic Biol Med 1999,
27: 146-159 |
|
Qian, Steven Yue et al. |
Iron and Dioxygen Chemistry
Is an Important Route to Initiation of Biological Free Radical Oxidations:
An Electron Paramagnetic Resonance Spin Trapping Study Free Radic
Biol Med 1999, 26: 1447-1456 |
|
Venkataraman, Sujatha et al. |
Detailed Methods
for the Quantification of Nitric Oxide in Aqueous Solutions Using Either
an Oxygen Monitor or EPR Free Radic Biol Med 2000, 29: 580-585 |
|
Kelley, Eric E. et al. |
Relative a-Tocopherol
Deficiency in Cultured Cells: Free Radical-Mediated Lipid Peroxidation,
Lipid Oxidizability, and Cellular Polyunsaturated Fatty Acid Content Arch Biochem Biophys 1995, 319: 102-109 |
|
Wagner, Brett A. et al. |
Vitamin E Slows the
Rate of Free Radical-Mediated Lipid Peroxidation in Cells Arch Biochem
Biophys 1996, 334: 261-267 |
|