Cholesterol, Low-Density Lipoprotein (calculated)

Label Mnemonic: LDLC
Epic code: LAB922
Order form: Laboratory Requisition
Supply order: Supply Order Form
Billing: Billing Policies
Specimen(s):
Plasma
Collection Medium:
Plasma Separator Tube 4.5 mL
Alternate Collection Media:
Call laboratory for additional acceptable specimen collection containers.
Minimum:

3 mL whole blood from light green top tube or ONE Microtainer®.

Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around Time:
1 hour (upon receipt in laboratory)
Reference Range:

<130 mg/dL (Approved by NCEP, National Cholesterol Education Program for adults 18 years and older)

Normal - <100 mg/dL
Above Normal - 100-129 mg/dL
Borderline High - 130-159 mg/dL
High - 160-189 mg/dL
Very High - ≥190 mg/dL

 

The Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents has set the following guidelines for lipids in a context of cardiovascular risk for children 2 to 17 years old:

 

LDL CHOLESTEROL

Acceptable: <110 mg/dL

Borderline High: 110-129 mg/dL

High: > or =130 mg/dL

 

Reference values have not been established for patients who are younger than 24 months of age.

Comments:

Fasting for at least 8 hours prior to collection is recommended. Cholesterol, Triglyceride and HDL Cholesterol must all be ordered for the Calculated LDL to be completed. The LDL Calculation cannot be done if Triglyceride value > 400 mg/dL. EDTA plasma causes decreased values.

 

References

  1. Jacobson TA, Ito MK, Maki KC, et al: National Lipid Association recommendations for patient-centered management of dyslipidemia: Part 1-executive summary. J Clin Lipidol. 2014;8(5):473-488. doi: 10.1016/j.jacl.2014.07.007

  2. Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents; National Heart, Lung, and Blood Institute: Expert panel on integrated guidelines for cardiovascular health and risk reduction in children and adolescents: Summary report. Pediatrics. 2011 Dec;128 Suppl 5(Suppl 5):S213-S256. doi: 10.1542/peds.2009-2107C
Methodology:

Calculated

Sample Processing:
Centrifuge at a speed and time necessary to get barrier separation of plasma/serum and cells.
Separate plasma or serum into labeled container and cap.
Sample Storage:
Refrigerate.
Transport Instructions:
Place labeled specimen into zip-lock type biohazard bag; seal bag.
Place completed requisition into outside pocket of bag.
Transport in cooler with refrigerated coolant packs.
 
See also:
Low Density Cholesterol Measured, Plasma
 
See Additional Information:
Fasting Specimen Requirements