| Label Mnemonic: | AML |
| Epic code: | LAB9075 |
| Order form: | Molecular Oncology Requisition |
| Supply order: | Supply Order Form |
| Billing: | Billing Policies |
| CPT code: | 81450 |
Blood, Bone Marrow Aspirate, or Formalin Fixed Paraffin Embedded Clot block (or 10 unstained 4-8 micron thick sections on non-plus slides and an H&E slide of the clot)
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| Pink top tube 6 mL (K2-EDTA) |
3 mL blood -OR- bone marrow in a pink EDTA top tube. Requires dedicated tube for molecular only.
Specimen requires 20% or greater tumor cell content. Submit formalin fixed paraffin embedded tissue and ten unstained 4 micron-thick sections on non-plus slides.
Specimens fixed in B5 fixative or decalcified will not be accepted. Tumor specimens containing less than 20% tumor cells may be unacceptable.
Twice Weekly
10-14 days upon receipt in laboratory
The Acute Myelogenous Leukemia Profiling test is a massively parallel next generation DNA sequencing-based assay that targets cancer-related genes.
Genes Assessed: ANKRD26, ASXL1, BCOR*, BRAF, CBL, CEBPA*, DDX41, DNMT3A, EZH2, FLT3, GATA2, HRAS, IDH1, IDH2, JAK2, KIT, KRAS, KMT2A* (MLL), NF1*, NPM1, NRAS, PHF6*, PPM1D, PTEN*, PTPN11, RUNX1*, SETBP1, SF3B1, SRSF2, STAG2*, TET2*, TP53, U2AF1, UBA1, WT1 and ZRSR2*.
Sequencing is limited to targeted gene regions unless marked with an Asterix indicating full coding sequence coverage.
Read more....
Massively parallel Next Generation DNA sequencing by synthesis
Specimen requires 20% or greater tumor cell content.
Recommend early AM overnight shipping or equivalent if not on courier service.
Ship refrigerated.
Place requisition into outside pocket of bag.
Protect phlebotomy tube from excessive heat and ship in cooled container during summer months.