gp 210 IgG

Label Mnemonic:	GP210
Epic code:	LAB8732
Order form:	Laboratory Requisition
Supply order:	Supply Order Form
Billing:	Billing Policies
CPT code:	83516

Specimen(s):

Serum

Collection Medium:

Red top tube 5 mL (Clot Activator)

Minimum:

Preferred Minimum: 1.0 mL serum in red top tube
Absolute Minimum: 0.1 mL serum in red top tube

Rejection Criteria:

Contaminated or heat-inactivated specimens.

Testing Schedule:

Test performed on Wednesdays.

Turn Around Time:

1-8 days upon receipt at reference laboratory.

Reference Range:

20.0 Units or less       Negative
20.1-24.9 Units          Equivocal
25.0 Units or greater    Positive

Interpretive Data:

GP210 IgG antibodies can be detected in patients with primary biliary cholangitis (PBC) and may be of diagnostic relevance in a subset of patients with PBC who are negative for anti-mitochondrial antibodies (AMA). These antibodies have a relatively low sensitivity with excellent specificity for PBC. A negative result does not rule out PBC.

Methodology:

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Sample Processing:

Allow to clot completely at room temperature. Separate serum from cells ASAP.
Centrifuge within two hours of draw time.
Label transport tube with patient last name, first name, identification number, date and time of collection.
Transfer serum into new screw-capped plastic vial.

Sample Storage:

Store frozen.

Transport Instructions:

Place labeled specimen into zip-lock type biohazard bag; seal bag.
Place completed requisition into outside pocket of bag.
Place dry ice on top of specimen in Styrofoam container to maintain frozen temperature.