Rapid Plasma Reagin (RPR) with Reflex Confirmation
Label Mnemonic: | RPRP |
Epic code: | LAB8647 |
Order form: | Laboratory Requisition |
Supply order: | Supply Order Form |
Billing: | Billing Policies |
CPT code: | 86592 |
Specimen(s):
Serum
Minimum:
5 mL serum from a BD Gold SST tube
Turn Around Time:
1 day
Reference Range:
Negative
Comments:
This testing consists of RPR with reflex to titer and TP-PA
confirmation. Additional charges apply if TP-PA confirmation is
performed.
This is generally not the preferred test for syphilis screening but may be indicated in some clinical situations. Syphilis Total Antibodies with Reflex Confirmation (LAB8631) is recommended for routine syphilis testing.
This is generally not the preferred test for syphilis screening but may be indicated in some clinical situations. Syphilis Total Antibodies with Reflex Confirmation (LAB8631) is recommended for routine syphilis testing.
Test Limitations:
The assay is unaffected by icterus < 66 mg/dL, hemolysis (Hb <
500 mg/dL), or lipemia < 2000 mg/dL). RPR assay interference
resulting in false positive results may occur with cross-reacting
antibodies from patients diagnosed with systemic lupus
erythematosus, malaria, autoimmune disease, viral pneumonia, and
people who have been recently vaccinated (including vaccines for
SARS-CoV-2). RPR results should be interpreted in conjunction with
patient history, risk factors, and other syphilis testing.
Methodology:
Multiplex flow immunoassay
Sample Processing:
Centrifuge at a speed and time necessary to get barrier separation
of plasma/serum and cells within 1 hour of collection. Send specimen
in original tube. Do Not transfer to another tube.
Each sample must be labeled with at least TWO full patient identifiers (First/Last Name & DOB are sufficient for non-UIHC affiliated clients) to avoid sample rejection/delays.
Each sample must be labeled with at least TWO full patient identifiers (First/Last Name & DOB are sufficient for non-UIHC affiliated clients) to avoid sample rejection/delays.
Sample Storage:
Store frozen.
All sample storage requirements are intended for delivery to UIHC within 24 hours of collection for testing. If samples won't arrive in this time period, please call the UIHC Core Lab for alternative storage/shipping instructions (319-356-3527).
All sample storage requirements are intended for delivery to UIHC within 24 hours of collection for testing. If samples won't arrive in this time period, please call the UIHC Core Lab for alternative storage/shipping instructions (319-356-3527).
Transport Instructions:
Place labeled specimen into zip-lock type biohazard bag; seal
bag.
Place completed requisition into outside pocket of bag.
Ship frozen.
Place completed requisition into outside pocket of bag.
Ship frozen.
See also:
Syphilis Total Antibodies with Reflex Confirmation, Serum
Syphilis Total Antibodies with Reflex Confirmation, Serum