Meningitis/Encephalitis Panel
| Label Mnemonic: | MENPANEL |
| Epic code: | LAB8514 |
| Order form: | Microbiology/Molecular Infectious Disease Requisition |
| Supply order: | Supply Order Form |
| Billing: | Billing Policies |
| CPT code: | 87483 |
Specimen(s):
CSF, Lumbar puncture
Collection Medium:
)
|
| CSF collection kit |
Minimum:
Collect in CSF container. A minimum volume of 1 mL CSF required in
addition to volume required for other tests run on the same
specimen. Transport to Microbiology Laboratory immediately.
•Cryptococcus PCR lacks sensitivity and cannot fully rule out
cryptococcal meningitis; Cryptococcus antigen (Epic LAB2233) may
be ordered if rapid testing is desired.
•Enterovirus testing includes Coxsackievirus A/B, Echovirus, and
Enterovirus, including EV-D68, EV-D70 and EV-D71. Bacterial culture,
Gram stain and susceptibility testing are always performed with this order.
•Pretreatment may result in a PCR-positive, culture negative
result.
•For interpretation of positive results, please see specific
comments appended to individual patient reports.
*If inpatient, only one panel allowed per visit without prior
approval. Please contact Microbiology Laboratory for approval.
•Cryptococcus PCR lacks sensitivity and cannot fully rule out
cryptococcal meningitis; Cryptococcus antigen (Epic LAB2233) may
be ordered if rapid testing is desired.
•Enterovirus testing includes Coxsackievirus A/B, Echovirus, and
Enterovirus, including EV-D68, EV-D70 and EV-D71. Bacterial culture,
Gram stain and susceptibility testing are always performed with this order.
•Pretreatment may result in a PCR-positive, culture negative
result.
•For interpretation of positive results, please see specific
comments appended to individual patient reports.
*If inpatient, only one panel allowed per visit without prior
approval. Please contact Microbiology Laboratory for approval.
Rejection Criteria:
CSF collected from indwelling medical devices are not acceptable,
Aerobic culture (LAB4801) should be ordered for these specimen
types.
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around Time:
6 hours (upon receipt in laboratory)
Reference Range:
Not Detected
Comments:
The FilmArray meningitis/encephalitis panel is a multiplex PCR test
capable of qualitatively detecting DNA or RNA of 14 pathogens
(bacteria and viruses).
The panel is used to diagnose infection caused by Escherichia coli, Haemophilus influenzae, Listeria monocytogenes, Neisseria meningitidis, Streptococcus agalactiae, Streptococcus pneumoniae, Cytomegalovirus (CMV), Enterovirus (including Coxsackievirus A/B, Echovirus, and Enterovirus, including EV-D68, EV-D70 and EV-D71), Human herpesvirus 6 (HHV-6), Herpes simplex virus 1 (HSV-1), Herpes simples virus 2 (HSV-2), Human parechovirus, Varicella zoster virus, and Cryptococcus neoformans/gattii.
The panel is used to diagnose infection caused by Escherichia coli, Haemophilus influenzae, Listeria monocytogenes, Neisseria meningitidis, Streptococcus agalactiae, Streptococcus pneumoniae, Cytomegalovirus (CMV), Enterovirus (including Coxsackievirus A/B, Echovirus, and Enterovirus, including EV-D68, EV-D70 and EV-D71), Human herpesvirus 6 (HHV-6), Herpes simplex virus 1 (HSV-1), Herpes simples virus 2 (HSV-2), Human parechovirus, Varicella zoster virus, and Cryptococcus neoformans/gattii.
Methodology:
PCR amplification; FilmArray ME Panel
Instructions:
Specimens should be received same day of collection.
Sample Processing:
Label transport tube with two patient identifiers, date and time of
collection.
Maintain sterility and forward promptly to lab.
Specimen should be collected and packaged as close to shipping time as possible.
Maintain sterility and forward promptly to lab.
Specimen should be collected and packaged as close to shipping time as possible.
Sample Storage:
Room Temperature.
Transport Instructions:
Place requisition into outside pocket of bag.
Place specimen into zip-lock type bag, seal bag.
DO NOT FREEZE, protect specimen by wrapping in bubble-wrap or toweling.
Recommend early AM overnight shipping or equivalent if not on courier service.
Place specimen into zip-lock type bag, seal bag.
DO NOT FREEZE, protect specimen by wrapping in bubble-wrap or toweling.
Recommend early AM overnight shipping or equivalent if not on courier service.
Zcode:
ZB4JW