Opiates

Label Mnemonic:	OPIU
Epic code:	LAB7385
Order form:	Laboratory Requisition
Supply order:	Supply Order Form
Billing:	Billing Policies
CPT code:	80361

Specimen(s):

Urine Screen

Collection Medium:

Clear top tube

Alternate Collection Media:

Urine (Random)-BD Vacutainer^®, no additive yellow top

Minimum:

5 mL random urine

Rejection Criteria:

Test cannot be added to a urine sample previously utilized for urinalysis testing (LAB1160, LAB1164, LAB8379).

Testing Schedule:

24 hrs/day, 7 days a week, including holidays.

Turn Around Time:

1 hour (upon receipt in laboratory)

Reference Range:

None

Interpretive Data:

Drug of abuse screening tests are to be used for medical purposes only and not for non-medical purposes (e.g., employee, competitive athlete, or forensic testing).

Comments:

Screen includes opiates only.  For full drug of abuse-urine 

panel, see "Drugs of Abuse Screen".



If quantitative confirmation is needed for opiates, call UIDL Client Services at 

1-866-844-2522. Allow up to seven days for confirmatory results. 


Quantitative confirmation is at an additional charge.



Approximate cut-off concentrations (ng/mL)

-----------------------------------------

Buprenorphine                 No cross-reactivity

Codeine                               224

6-Acetylmorphine (heroin metabolite)  386

Fentanyl                      No cross-reactivity

Heroin                                366

Hydrocodone                         1,086

Hydromorphone                       1,425

Meperidine                      > 100,000

Methadone                     No cross-reactivity

Morphine                              300

Oxycodone*                       > 75,000



*Therapeutic use of oxycodone in the absence of any other opiates is 

unlikely to result in a positive opiates screen.





References:



Belson MG, Simon HK, Sullivan K, Geller RJ.  The Utility of 

Toxicologic Analysis in Children with Suspected Ingestion.  Pediatr 

Emerg Care 1999;15:383-387.



Bast RP, Helmer SD, Henderson SR, Rogers MA, Shapiro WM, Smith RS.  

Limited Utility of Routine Drug Screening in Trauma Patients.  South 

Med J 2000;93:397-399.



Hammett-Stabler CA, Pesce AJ, Cannon DJ.  Urine Drug Screening in the 

Medical Setting.  Clinica Chimica Acta 2002;315:125-135.



Schiller MJ, Shumway M, Batki SL.  Utility of Routine Drug Screening 

in a Psychiatric Emergency Setting.  Psychiatric Services 2000;51:474-

478.



Sugarman JM, Rodgers GC, Paul RI.  Utility of Toxicology Screening in 

a Pediatric Emergency Department.  Pediatric Emergency Care.  

Pediatric Emergency Care 1997;13(3):194-197.

Test Limitations:

There is the possibility that other substances and/or factors may interfere with the test and cause erroneous results (e.g., technical or procedural errors). Call the lab at 319-356-3527 for additional information.

Methodology:

Assay is based on the kinetic interaction of microparticles in a solution (KIMS) as measured by changes in light transmission.

Sample Processing:

Submit in leak-proof container.
Label transport tube with two patient identifiers, date and time of collection.

Sample Storage:

Refrigerate.

Transport Instructions:

Place labeled specimen into zip-lock type biohazard bag; seal bag.
Place completed requisition into outside pocket of bag.
Transport in cooler with refrigerated coolant packs.

See also:
Drugs of Abuse, Urine
Drugs of Abuse, Urine + Confirm