Benzodiazepines
| Label Mnemonic: | BZOU |
| Epic code: | LAB7382 |
| Order form: | Laboratory Requisition |
| Supply order: | Supply Order Form |
| Billing: | Billing Policies |
| CPT code: | 80346 |
Specimen(s):
Urine Screen
Collection Medium:
) |
| Clear top tube |
Alternate
Collection Media:
Urine (Random)-BD Vacutainer®, no additive yellow top
Minimum:
5 mL random urine
Rejection Criteria:
Test cannot be added to a urine sample previously utilized for urinalysis testing (LAB1160, LAB1164, LAB8379).
Testing
Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around
Time:
1 hour (upon receipt in laboratory)
Reference Range:
None
Interpretive Data:
Drug of abuse screening tests are to be used for medical purposes only and not for non-medical purposes (e.g., employee, competitive athlete, or forensic testing).
Comments:
Screen includes benzodiazepines only. For full drug of abuse- urine panel, see Drug of Abuse Screen. If quantitative confirmation is needed for benzodiazepines, call UIDL Client Services at 1-866-844-2522. Allow up to seven days for confirmatory results.
Quantitative confirmation is at an additional charge. Additional information on approximate cut-offs for individual drugs or drug metabolites in the specific assays BENZODIAZEPINES ASSAY Drug Approximate cut-off for benzodiazepines assay (ng/mL) ------------------------------------------------------------- Alprazolam* 92 Bentazepam 128 Bromazepam 76 Brotiazolam 138 Chlordiazepoxide 109 Clobazam 95 Clonazepam* 103 Clonazolam 110 Clorazepate 189 Delorazepam 109 Demoxepam 76 Deschloroetizolam 81 Diazepam 90 Diclazepam 99 Estazolam 88 Etizolam 118 Flubromazepam 132 Flubromazolam 105 Flunitrazepam 113 Flurazepam 161 Halazepam 132 Lorazepam 105 Lormetazepam 107 Meclonazepam 123 Medazepam 138 Midazolam 106 Nifoxipam 129 Nimetazepam 96 Nitrazepam 96 Oxazepam 89 Phenazepam 124 Pinazepam 110 Prazepam 124 Pyrazolam 103 Temazepam 94 Tetrazepam 116 Triazolam 103 *In patients taking typical therapeutic doses of these benzodiazepines for medical purposes, the benzodiazepines screen can be negative due to the low concentrations of these drugs and their metabolites excreted in urine relative to the cut-offs. Assay with improved detection of glucuronidated benzodiazepines implemented 05-21-2024. References: Belson MG, Simon HK, Sullivan K, Geller RJ. The Utility of Toxicologic Analysis in Children with Suspected Ingestion. Pediatr Emerg Care 1999;15:383-387. Bast RP, Helmer SD, Henderson SR, Rogers MA, Shapiro WM, Smith RS. Limited Utility of Routine Drug Screening in Trauma Patients. South Med J 2000;93:397-399. Hammett-Stabler CA, Pesce AJ, Cannon DJ. Urine Drug Screening in the Medical Setting. Clinica Chimica Acta 2002;315:125-135. Schiller MJ, Shumway M, Batki SL. Utility of Routine Drug Screening in a Psychiatric Emergency Setting. Psychiatric Services 2000;51:474- 478. Sugarman JM, Rodgers GC, Paul RI. Utility of Toxicology Screening in a Pediatric Emergency Department. Pediatric Emergency Care. Pediatric Emergency Care 1997;13(3):194-197.
Test
Limitations:
There is the possibility that other substances and/or factors may interfere with the test and cause erroneous results (e.g., technical or procedural errors). Call the lab at 319-356-3527 for additional information.
Methodology:
Assay is based on the kinetic interaction of microparticles in a solution (KIMS) as measured by changes in light transmission.
Sample
Processing:
Submit urine in leak-proof plastic container.
Label transport tube with two patient identifiers, date and time of collection.
Label transport tube with two patient identifiers, date and time of collection.
Sample
Storage:
Refrigerate.
Transport
Instructions:
Place labeled specimen into zip-lock type biohazard bag; seal bag.
Place completed requisition into outside pocket of bag.
Transport in cooler with refrigerated coolant packs.
Place completed requisition into outside pocket of bag.
Transport in cooler with refrigerated coolant packs.