Tobramycin Drug Level
Label Mnemonic: | TOB |
Epic code: | LAB36 |
Order form: | Laboratory Requisition |
Supply order: | Supply Order Form |
Billing: | Billing Policies |
CPT code: | 80200 |
Specimen(s):
Plasma
Collection Medium:
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Plasma Separator Tube 4.5 mL |
Alternate Collection Media:
Call laboratory for additional acceptable specimen collection
containers.
Minimum:
3 mL whole blood in light green top or ONE Microtainer®.
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around Time:
1 hour (upon receipt in laboratory)
Reference Range:
Peak 6-10 μg/mL; (45-75 min. after I.M. dose, 15-30 min. after I.V. dose) Trough <2 μg/mL; (Not more than 30 min. before next dose) Critical value: Peak >10 μg/mL
Comments:
Phlebotomy team does not draw timed tobramycin specimens. Clinical
staff must draw accurately timed peak and trough specimens.
Test Limitations:
Icterus: No significant interference from bilirubin up to an I index of 30. Hemolysis: No significant interference from hemoglobin up to an H index of 800. Lipemia (Intralipid): No significant interference up to an L index of 750. There is poor correlation between turbidity and triglycerides concentration. No significant interference from total protein up to 12 g/dL.
Methodology:
Homogenous Enzyme Immunoassay
Sample Processing:
Centrifuge at a speed and time necessary to get barrier separation
of plasma/serum and cells within 1 hour of collection. Send specimen
in original tube. Do Not transfer to another tube.
Each sample must be labeled with at least TWO full patient identifiers (First/Last Name & DOB are sufficient for non-UIHC affiliated clients) to avoid sample rejection/delays.
Each sample must be labeled with at least TWO full patient identifiers (First/Last Name & DOB are sufficient for non-UIHC affiliated clients) to avoid sample rejection/delays.
Sample Storage:
Refrigerate.
Transport Instructions:
Place labeled specimen into zip-lock type biohazard bag; seal
bag.
Place completed requisition into outside pocket of bag.
Transport in cooler with refrigerated coolant packs.
Place completed requisition into outside pocket of bag.
Transport in cooler with refrigerated coolant packs.
See Additional Information:
Chemistry Critical Lab Values
Chemistry Critical Lab Values