Cadmium, Random Urine
| Label Mnemonic: | CDUR |
| Epic code: | LAB8528 |
| Downtime form: | Doctor/Provider Orders - Pathology Core and Specialty Care Nursery |
6240-8 RCP
356-8593
Patient Prep: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician). High concentrations of iodine may interfere with elemental testing. Abstinence from iodine-containing medications or contrast agents for at least 1 month prior to collecting specimens for elemental testing is recommended.
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| Urine (Random)-BD Vacutainer®, no additive yellow top |
Preferred Minimum: 8 mL random urine
Absolute Minimum: 1 mL random urine
Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media (may occur with MRI studies). Acid preserved urine.
1–5 days upon receipt at reference laboratory
| Components | Reference Interval |
|---|---|
| Cadmium, Urine - per volume | Less than or equal to 1.0 microg/L |
| Cadmium, Urine - ratio to CRT | Less than or equal to 3.2 microg/g CRT |
Urine cadmium concentrations can be used to assess cadmium body burden. In chronic exposures, the kidneys are the primary target organ. Symptoms associated with cadmium toxicity vary based upon route of exposure and may include tubular proteinuria, fever, headache, dyspnea, chest pain, conjunctivitis, rhinitis, sore throat and cough. Ingestion of cadmium in high concentration may cause vomiting, diarrhea, salivation, cramps, and abdominal pain.
Elevated results may be due to skin or collection-related contamination, including the use of collection containers that are not certified to be trace element-free. If an elevated result is suspected to be due to contamination, confirmation with a second specimen collected in a certified trace element-free container is recommended.
Quantitative Inductively Coupled Plasma-Mass Spectrometry