West Nile Virus Antibody, IgM
| Label Mnemonic: | WNIGMCSF |
| Epic code: | LAB8521 |
| Downtime form: | Doctor/Provider Orders - Pathology Core and Specialty Care Nursery |
Commercial Mailout Laboratory
6240-8 RCP
356-8593
6240-8 RCP
356-8593
Specimen(s):
CSF
Collection Medium:
) |
| CSF collection kit |
Minimum:
Preferred Minimum: 2 mL CSF in CSF container
Absolute Minimum: 0.15 mL CSF
Absolute Minimum: 0.15 mL CSF
Rejection Criteria:
Contaminated, heat-inactivated, or hemolyzed specimens.
Turn Around
Time:
1-6 days upon receipt at reference laboratory
Reference Range:
0.89 IV or less: Negative - No significant level of West Nile virus
IgM antibody detected.
0.90-1.10 IV: Equivocal - Questionable presence of West Nile virus IgM antibody detected. Repeat testing in 10-14 days may be helpful.
1.11 IV or greater: Positive - Presence of IgM antibody to West Nile virus detected, suggestive of current or recent infection.
0.90-1.10 IV: Equivocal - Questionable presence of West Nile virus IgM antibody detected. Repeat testing in 10-14 days may be helpful.
1.11 IV or greater: Positive - Presence of IgM antibody to West Nile virus detected, suggestive of current or recent infection.
Interpretive Data:
This test is intended to be used as a semi-quantitative means of
detecting West Nile virus-specific IgM in CSF specimens in which there
is a clinical suspicion of West Nile virus infection. This test should
not be used solely for quantitative purposes, nor should the results
be used without correlation to clinical history or other data. Because
other members of the Flaviviridae family, such as St. Louis
encephalitis virus, show extensive cross-reactivity with West Nile
virus, serologic testing specific for these species should be
considered.
The detection of antibodies to West Nile virus in cerebrospinal fluid may indicate central nervous system infection. However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier.
The detection of antibodies to West Nile virus in cerebrospinal fluid may indicate central nervous system infection. However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier.
Comments:
This is the preferred test for diagnosing West Nile encephalitis.
Methodology:
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
CPT Code:
86788