IGH Variable Region Mutation Analysis

Label Mnemonic:	IGHVBM
Epic code:	LAB7503
Downtime form:	Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Commercial Mailout Laboratory
6240-8 RCP
356-8593

Specimen(s):

Bone Marrow

Minimum:

3 mL (EDTA) bone marrow.

Rejection Criteria:

Frozen or clotted specimens.

Delivery Instructions:

Deliver to laboratory immediately after collection. Refrigerated specimens should be received within 48 hours of collection for optimal viability.

Testing Schedule:

Monday-Thursday and Friday until Noon, no weekends, no holidays.

Turn Around Time:

12-14 days upon receipt at reference laboratory.

Interpretive Data:

Refer to report.

Comments:

This mailout test requires pathologist approval for orders during inpatient encounters. Mailouts staff will not process order without approval. The pathologist covering mailouts approval can be reached at pager #3724. If approval is given, the name of the pathologist can be selected in the drop-down menu to the right of the approval warning in Epic when ordering the test.

This assay is designed for individuals with a confirmed diagnosis of CLL, and for these individuals testing will include sequencing. All other diagnoses will terminate after amplification and will not have the sequencing component.

Test indicated for chronic lymphocytic leukemia (CLL) prognosis; prior diagnosis of CLL should be obtained.

Methodology:

Polymerase Chain Reaction/Sequencing

CPT Code:

81263