Vanillylmandelic Acid
| Label Mnemonic: | VMAUR |
| Epic code: | LAB7402 |
| Downtime form: | Doctor/Provider Orders - Pathology Core and Specialty Care Nursery |
Commercial Mailout Laboratory
6240-8 RCP
356-8593
6240-8 RCP
356-8593
Specimen(s):
Random Urine
Collection Medium:
) |
| Yellow top round bottom tube (no additive) |
Minimum:
Preferred Minimum: 4 mL random urine
Absolute Minimum: 1 mL random urine
Abstain from medications for 72 hours prior to collection.
Absolute Minimum: 1 mL random urine
Abstain from medications for 72 hours prior to collection.
Turn Around
Time:
1-5 days upon receipt at reference laboratory
Reference Range:
Components Age Ref. Interval
Vanillylmandelic 18 years and older 0.0-7.0 mg/d
Acid - per 24 hr
Vanillylmandelic The VMA-to-creatinine ratio will be reported when
Acid - Ratio the patient is under 18 years or the urine volume
to CRT is less than 400 mL/24 hours.
Vanillylmandelic 0-2 years 0-27 mg/g CRT
Acid - Ratio 3-5 years 0-13 mg/g CRT
to CRT 6-17 years 0-9 mg/g CRT
18 years and older 0-6 mg/g CRTInterpretive Data:
Vanillylmandelic acid (VMA) results are expressed as a ratio to
creatinine excretion (mg/g cr). VMA mass per day (mg/d) is not reported
on specimens from patients younger than 18 years of age, for random
specimens, urine collection periods other than 24 hours, or for urine
volumes less than 400 mL/d. No reference interval is available for
results reported in units of mg/L.
Comments:
Moderately elevated VMA (vanillylmandelic acid) can be caused by a
variety of factors such as essential hypertension, intense anxiety,
intense physical exercise, and numerous drug interactions (including
some over-the-counter medications and herbal products).
Medications that may interfere with catecholamines and their metabolites include amphetamines and amphetamine-like compounds, appetite suppressants, bromocriptine, buspirone, caffeine, chlorpromazine, clonidine, disulfiram, diuretics (in doses sufficient to deplete sodium), epinephrine, glucagon, guanethidine, histamine, hydrazine derivatives, imipramine, levodopa (L-dopa, Sinemet®), lithium, MAO inhibitors, melatonin, methyldopa (Aldomet®), morphine, nitroglycerin, nose drops, propafenone (Rythmol), radiographic agents, rauwolfia alkaloids (Reserpine), tricyclic antidepressants, and vasodilators. The effects of some drugs on catecholamine metabolite results may not be predictable.
Medications that may interfere with catecholamines and their metabolites include amphetamines and amphetamine-like compounds, appetite suppressants, bromocriptine, buspirone, caffeine, chlorpromazine, clonidine, disulfiram, diuretics (in doses sufficient to deplete sodium), epinephrine, glucagon, guanethidine, histamine, hydrazine derivatives, imipramine, levodopa (L-dopa, Sinemet®), lithium, MAO inhibitors, melatonin, methyldopa (Aldomet®), morphine, nitroglycerin, nose drops, propafenone (Rythmol), radiographic agents, rauwolfia alkaloids (Reserpine), tricyclic antidepressants, and vasodilators. The effects of some drugs on catecholamine metabolite results may not be predictable.
Methodology:
High Performance Liquid Chromatography - Tandem Mass Spectrometry
CPT Code:
84585
See also:
Catecholamines, Fractionated, Random Urine
Homovanillic Acid, Random Urine
Metanephrines Total, Random Urine
Catecholamines, Fractionated, Random Urine
Homovanillic Acid, Random Urine
Metanephrines Total, Random Urine
See Additional Information:
Urine Tests Requiring no Preservatives
Urine Tests Requiring no Preservatives