Herpes Virus 7 (HHV-7) Quant.

Label Mnemonic:	HHV7
Epic code:	LAB3315
Downtime form:	Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Commercial Mailout Laboratory
6240-8 RCP
356-8593

Specimen(s):

Plasma

Collection Medium:

Pink top tube 6 mL (K2-EDTA)

Alternate Collection Media:

Lavender top tube 3 mL (EDTA)

Minimum:

2 mL plasma collected in EDTA (pink top) tube

Rejection Criteria:

Whole blood frozen.

Turn Around Time:

24 hours upon receipt in reference laboratory.

Reference Range:

Not detected.

Comments:

HHV-7 is detectable in a variety of transplant settings, both HSCT 
and solid organ. Direct effects of HHV-7 include fever, rash, 
myelosuppression, encephalitis, and pneumonitis. Potentially more 
important are the indirect effects HHV-7 has on CMV disease, invasive 
fungal disease, and allograft dysfunction. Quantitative HHV-7 DNA PCR 
can be used to document the presence of the virus as well as track the 
course of infection.

The primers and probes used in this assay are specific for known 
strains of HHV-7 based on similarity search algorithms. Additionally, 
no cross reactivity was detected when tested against adenoviruses, BKV, 
CMV, EBV, HSV-1, HSV-2, HHV-6 variant A, HHV-6 variant B, HHV-8, JCV, 
parvovirus B19, SV-40, and VZV.

Methodology:

Quantitative Real-Time PCR

CPT Code:

87799