JAK2 Exons 12, 13, and 14 including V617F Mutation Analysis with Interpretation
| Label Mnemonic: | JAK2 |
| Epic code: | LAB2472 |
| Downtime form: | Doctor/Provider Orders - Pathology Molecular |
Molecular Pathology
6240 RCP
384-9568
6240 RCP
384-9568
Specimen(s):
Whole Blood
Collection Medium:
 |
| Pink top tube 6 mL (K2-EDTA) |
Minimum:
Adults 3 mL whole blood. Testing on smaller volumes than those requested will be attempted. However, in some cases, small blood volumes may compromise the ability to perform testing. Testing requires a dedicated collection tube.
Delivery Instructions:
Room temperature for up to 24 hours, then refrigerate
the whole blood if it is necessary to be held overnight,
weekends or holidays.
Testing Schedule:
Weekly
Turn Around
Time:
7-10 working days upon receipt
Reference Range:
Direct detection of G-T transversion at position 1849 of the Janus kinase 2 locus, giving rise to a Valine-to-Phenylalanine substitution at position 617 (JAK2 V617F mutation).
Interpretive Data:
Refer to report
Methodology:
Massively parallel next generation DNA sequencing by synthesis, using semiconductor technology.
CPT Code:
81270
This test is useful for diagnosis of myeloproliferative disorders. Note: Exon 14 includes the common V617F variant.