Thyroid Peroxidase Antibody

Label Mnemonic: TPOAB
Epic code: LAB957
Downtime form: Doctor/Provider Orders - Pathology Core and Specialty Care Nursery
Chemistry
6240 RCP
356-3527
Specimen(s):
Plasma
Collection Medium:
Plasma Separator Tube 4.5 mL
Alternate Collection Media:
Call laboratory for additional acceptable specimen collection containers.
Minimum:

3 mL; plasma separator tube top or TWO Microtainer® devices.

Turn Around Time:
1 hour (upon receipt in laboratory)
Reference Range:

<= 34 IU/mL

Comments:

This assay may be significantly impacted by high-dose biotin (>5 mg dose) taken within previous 12 hours. High concentrations of biotin may lead to falsely increased results. These concentrations may be found in patients taking over-the-counter supplements with biotin content much higher than nutritional requirements for biotin. Specimens should not be collected until at least 12 hours after the last dose.

Test Limitations:

Hemolysis: No significant interference up to an H index of 1500.
Lipemia: No significant interference up to an L index of 2100.
Icterus: No significant interference up to an I index of 66.

Methodology:

Electrochemiluminescence Immunoassay

CPT Code:
86376
 
See Additional Information:
Biotin Interference with Immunoassays