Topiramate (Topir) Drug Level
| Label Mnemonic: | TOPR |
| Epic code: | LAB498 |
| Downtime form: | Doctor/Provider Orders - Pathology Core and Specialty Care Nursery |
Commercial Mailout Laboratory
6240-8 RCP
356-8593
6240-8 RCP
356-8593
Specimen(s):
Serum
Specimen
Instructions:
Timing of specimen collection: Pre-dose (trough) draw - At steady state
concentration.
Collection Medium:
 |
| Red top tube 5 mL (Clot Activator) |
Minimum:
Preferred Minimum: 1.0 mL serum
Absolute Minimum: 0.3 mL serum
Absolute Minimum: 0.3 mL serum
Rejection Criteria:
Gel separator tubes
Delivery Instructions:
Deliver to laboratory immediately after collection.Turn Around
Time:
Within 24 hours upon receipt at reference laboratory.
Reference Range:
Therapeutic range: 5.0-20.0 μg/mL Toxic: not well established
Interpretive Data:
The proposed therapeutic range for seizure control is 5-20 μg/mL.
Pharmacokinetics varies widely, particularly with co-medications, age,
and/or compromised renal function.
Methodology:
Quantitative Enzyme Immunoassay
CPT Code:
80201