Lead, 24-Hour Urine

Label Mnemonic:	UPB
Epic code:	LAB404
Downtime form:	Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Commercial Mailout Laboratory
6240-8 RCP
356-8593

Specimen(s):

24-hour urine More information

Specimen Instructions:

Refrigerate during 24 hr collection in plastic container. Reference laboratory studies indicate that refrigeration of urine alone, during and after collection, preserves specimens adequately, if tested within 14 days of collection.

Patient Prep: Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non- essential over-the-counter medications (upon the advice of their physician). High concentrations of iodine may interfere with elemental testing. Collection of urine specimens from patients receiving iodinated or gadolinium-based contrast media should be avoided for a minimum of 72 hours post-exposure. Collection from patients with impaired kidney function should be avoided for a minimum of 14 days post-contrast media exposure.

Collection Medium:

Urine - 24 hour/timed plastic urine container

Minimum:

Preferred Minimum: 8 mL aliquot from 24 hour collection.
Absolute Minimum: 1 mL aliquot from 24 hour collection.

Refrigerate during collection and submission.

Rejection Criteria:

Urine collected within 72 hours after administration of iodinated or gadolinium-based contrast media. Acid preserved urine. Specimens contaminated with blood or fecal material. Specimens transported in non-trace element free transport tube (with the exception of the original device).

Turn Around Time:

1–5 days upon receipt at reference laboratory

Reference Range:

Components

Reference Interval

Creatinine, Urine - per 24h

Age	Male (mg/d)	Female (mg/d)
3–8 years	140–700	140–700
9–12 years	300–1300	300–1300
13–17 years	500–2300	400–1600
18–50 years	1000–2500	700–1600
51–80 years	800–2100	500–1400
81 years and older	600–2000	400–1300

Lead, Urine - per 24h

Less than or equal to 8.1 microg/d

Lead, Urine - per volume

Less than or equal to 5.0 microg/L

Lead, Urine - ratio to CRT

Less than or equal to 5.0 microg/g CRT

Interpretive Data:

Per 24h calculations are provided to aid interpretation for collections with a duration of 24 hours and an average daily urine volume. For specimens with notable deviations in collection time or volume, ratios of analytes to a corresponding urine creatinine concentration may assist in result interpretation.

Elevated results may be due to skin or collection-related contamination, including the use of collection containers that are not certified to be trace element-free. If an elevated result is suspected to be due to contamination, confirmation with a second specimen collected in a certified trace element-free container is recommended.

Methodology:

Quantitative Inductively Coupled Plasma/Mass Spectrometry

CPT Code:

83655

See Additional Information:
Urine Tests Requiring Preservatives, Refrigeration or Special Containers