Jo-1 Antibody

Label Mnemonic:	JO1
Epic code:	LAB3455
Downtime form:	Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Chemistry
6240 RCP
356-3527

Specimen(s):

Plasma

Collection Medium:

Plasma Separator Tube 4.5 mL

Alternate Collection Media:

Call laboratory for additional acceptable specimen collection containers.

Minimum:

3.0 mL whole blood from light green top tube or TWO Microtainer^® devices

Testing Schedule:

24 hrs/day, 7 days a week, including holidays.

Turn Around Time:

3 hours (upon receipt in laboratory)

Reference Range:

1.0 AI (antibody index) or less

Interpretive Data:

Jo-1 antibodies are a marker for polymyositis and occur most commonly in myositis patients with interstitial lung disease. Jo-1 antibodies occur in 50% or more of patient with interstitial pulmonary fibrosis and symmetrical polyarthritis. A negative result for Jo-1 antibodies does not rule out polymyositis.

Comments:

Assay methodology and reference ranges changed February 25, 2013.

Methodology:

Multiplex flow immunoassay

CPT Code:

86235