Immunoglobulin G (IgG), Individual Quant

Label Mnemonic:	IGG
Epic code:	LAB71
Downtime form:	Doctor/Provider Orders - Pathology Core and Specialty Care Nursery

Chemistry
6240 RCP
356-3527

Specimen(s):

Plasma

Collection Medium:

Plasma Separator Tube 4.5 mL

Alternate Collection Media:

Call laboratory for additional acceptable specimen collection containers.

Minimum:

3 mL whole blood from light green top tube or ONE Microtainer^®.

Testing Schedule:

24 hrs/day, 7 days a week, including holidays.

Turn Around Time:

1 hour (upon receipt in laboratory)

Reference Range:

700-1600 mg/dL

Children and Juveniles
 0-1 year    232-1411 mg/dL
 1-3 years   453-916  mg/dL
 4-6 years   504-1465 mg/dL
 7-9 years   572-1474 mg/dL
10-11 years  698-1560 mg/dL
12-13 years  759-1550 mg/dL
14-15 years  716-1711 mg/dL
16-19 years  549-1584 mg/dL

Soldin JS, Brugnara C, Wong EC. Pediatric Reference Intervals. AACC Press. 2005, 5th ed., p. 42.

Test Limitations:

Criterion: Recovery within plus or minus 10% of initial values.

Icterus: No significant interference up to an I index of 60 
(approximate conjugated and unconjugated bilirubin concentration: 60 
mg/dL).

Hemolysis: No significant interference up to an H index of 1000. 
(approximate hemoglobin concentration: 1000 mg/dL)

Lipemia (Intralipid): No significant interference up to an L index of 
2000.

There is poor correlation between turbidity and triglycerides 
concentration.

There is no cross-reaction between IgG, IgA and IgM under the assay 
conditions.

Sera with ill-defined clinical characteristics should first be 
subjected to protein electrophoresis so that an antigen excess (e.g. 
gammopathy), if present, can be identified.

IgG concentrations of more than 40,000 mg/dL (400 g/L) can cause a 
high-dose hook effect.

Methodology:

Immunoturbidimetric

CPT Code:

82784