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Kimberly S. Ephgrave, MD

Professor of Surgery
Department of Surgery
Division of Gastrointestinal, Minimally-Invasive and Bariatric Surgery
kimberly-ephgrave@uiowa.edu
Office Telephone: 319-356-8435

Digestive Diseases Clinic
Telephone: 319-356-4061

Joseph Cullen image

Medical School:

  • Loyola-Stritch School of Medicine, Chicago IL

Internship:

  • Loyola University Medical Center, Maywood, IL

Residency:

  • Parkland Memorial Hospital, Dallas, TX

Certification:

  • American Board of Surgery, 1987, recertified 1995
  • Certificate of Added Qualifications in Critical Care, 1988; recertified 1997

Societies, Organizations, and Honors:

  • Alpha Omega Alpha
  • American Medical Women's Association Citation
  • Fellow, American College of Surgeons
  • Association of Academic Surgeons
  • Shock Society
  • Association of Surgical Education
  • American Gastroenterological Association
  • Society of Critical Care Medicine
  • Association of Women Surgeons, President, 2000-2001
  • Association of VA Surgeons; Secretary, 2000-2003
  • Central Surgical Association
  • Society of Critical Care Medicine
  • Society of University Surgeons Collegiate Teaching Award - 1992
  • College of Medicine Student Teacher of the year 1991, 1993, 1996
  • Surgery Research Award, Society of Critical Care Medicine - 1993
  • Outstanding Surgical Teacher Award, Association of Surgical Education, 1996
  • Louis Holloway Award for Excellence in Educational Research, 1996
  • Faculty Service Award, U. Iowa College of Medicine, 2001

Research Interests:

  • Gastric mucosal protection
  • Shock and multi-system organ failure
  • Pancreatic pseudocysts
  • Gastric motility
  • Surgical Education

Selected Recent Publications:

  • K Ephgrave, C. Kreiter, K Ferguson, B Goodwin. Team-based versus preceptor-based assignments of junior surgical clerks. Am J Surg 173:333-337, 1997.
  • D J Wirthlin, J J Cullen, S T Spates, J L Conklin, J Murray, D K Caropreso, K S Ephgrave Gastrointestinal transit during endotoxemia: The role of nitric oxide. J. Surg Res 60:307-311, 1996.
  • K. Ephgrave & F. Johlin, Case Report: Colon carcinoma arising after duodenocolic anatomosis. J Clin Gastro, 22:244-245, 1996.
  • K S Ephgrave, Konrad Schulze-Delrieu, J J Cullen, K Broadhurst, R. Kleiman-Wexler, S S Shirazi. The role of gastric contractions in cold restraint models of stress ulceration. Neurogastroenterology and Motility 9:187-192,1997.
  • K Ephgrave, T. Kremer, K. Broadhurst, J Cullen. The role of platelet activating factor (PAF) in conscious, normotensive endotoxemia. J. Surg Res 68:170-174,1997.
  • JJ Cullen, KS Ephgrave, DK Caropreso: Gastrointestinal myoelectric activity during endotoxemia. Am J of Surg 171:596-599, 1996.
  • JJ Cullen, LL Hemann, KS Ephgrave, MM Hinkhouse: Endotoxin temporarily impairs canine jejunal absorption of water, electrolytes, and glucose. J Gastro Surg, 1:286-291,1997.
  • JJ Cullen, DK Caropreso, KS Ephgrave, LL Hemann, MM Hinkhouse: The effect of endotoxin on canine jejunal motility and transit. J of Surg Res, 67:54-57, 1997.
  • JJ Cullen, DK Caropreso, LL Hermann, JL Conklin, KS Ephgrave: Pathophysiology of adynamic ileus Dig Dis Sci 42:731-737, 1997.
  • JJ Cullen, D Mercer, A Qalbani, M Hinkhouse, KS Ephgrave. The effects of endotoxin on regulation of intestinal smooth muscle nitric oxide synthase and intestinal transit. Surgical Forum 48:162-164, 1997.
  • JJ Cullen, ST Spates, KS Ephgrave, MM Hinkhouse. Endotoxin temporarily impairs canine colonic absorption of water and sodium. Journal of Surgical Research 74:34-38, 1998.
  • KS Ephgrave, K Brasel, JJ Cullen, K Broadhurst. Gastric Mucosal Protection from Enteral Nutrients: The Role of Motility. J Am Col Surg, 186:435-440, 1998.
  • K S Ephgrave, R Kleiman-Wexler, M Pfaller, B M Booth, D Reed, L Werkmeister, S Young. Effects of sucralfate vs antacids on gastric pathogens: Results of a double-blind clinical trial. Archives of Surgery 133:251-257, 1998.
  • ST Spates, JJ Cullen, KS Ephgrave, MM Hinkhouse. The effect of endotoxin on canine colonic motility and transit. Journal of Gastrointestinal Surgery (in press).
  • K S Ephgrave, K J Brasel, J J Cullen, K Broadhurst. Gastric mucosal protection from enteral nutrients: the role of motility. J Am Col Surg 186:434-440, 1998.
  • E Frank, M Brownstein, K S Ephgrave, L Neumayer. Characteristics of women surgeons in the United States. Am J Surg 176:3 244-250, 1998.
  • Spates ST. Cullen JJ. Ephgrave KS. Hinkhouse MM. Effect of endotoxin on canine colonic motility and transit. Journal of Gastrointestinal Surgery. 2(4):391-8, 1998 Jul-Aug.
  • J J Cullen, R Dotie, K S Ephgrave, M M Hinkhouse, K Broadhurst. Changes in intestinal transit and absorption during endotoxemia are dose-dependent. J of Surg Res 81:81-86, 1999.
  • J J Cullen, D W Mercer, A Qalbani, M M Hinkhouse, K S Ephgrave, J L Conklin. Effects of endotoxin on regulation of intestinal smooth muscle nitric oxide synthase and intestinal transit. Surgery, 125:339-344, 1999.
  • Ephgrave KS. Buchmiller C. Jones MP. Cullen JJ. The cup is half full. American Journal of Surgery. 178(5):406-10, 1999 Nov.
  • Cullen JJ. Titler S. Ephgrave KS. Hinkhouse MM. Gastric emptying of liquids and postprandial pancreatobiliary secretion are temporarily impaired during endotoxemia. Digestive Diseases & Sciences. 44(11):2172-7, 1999 Nov.
  • Cullen JJ. Conklin JL. Ephgrave KS. Oberley LW. The role of antioxidant enzymes in the control of opossum gallbladder motility. Journal of Surgical Research. 86(1):155-61, 1999 Sep.
  • Cullen JJ. Mercer D. Hinkhouse M. Ephgrave KS. Conklin JL. Effects of endotoxin on regulation of intestinal smooth muscle nitric oxide synthase and intestinal transit. Surgery. 125(3):339-44, 1999 Mar.
  • Cullen JJ. Doty RC. Ephgrave KS. Hinkhouse MM. Broadhurst K. Changes in intestinal transit and absorption during endotoxemia are dose dependent. Journal of Surgical Research. 81(1):81-6, 1999 Jan.
  • Cowl CT. Weinstock JV. Al-Jurf A. Ephgrave K. Murray JA. Dillon K. Complications and cost associated with parenteral nutrition delivered to hospitalized patients through either subclavian or peripherally-inserted central catheters. Clinical Nutrition. 19(4):237-43, 2000 Aug.
  • Frank E. Brownstein M. Ephgrave K. Neumayer L. Characteristics of women surgeons in the United States. American Journal of Surgery. 176(3):244-50, 1998 Sep.
  • Magrane D. Ephgrave K. Jacobs MB. Rusch R. Weaving women's health across clinical clerkships. Academic Medicine. 75(11):1066-70, 2000 Nov.
  • Cullen JJ. Maes EB. Aggrawal S. Conklin JL. Ephgrave KS. Mitros FA. Effect of endotoxin on opossum gallbladder motility: a model of acalculous cholecystitis. Annals of Surgery. 232(2):202-7, 2000 Aug.
  • Ephgrave KS. Scott DL. Ong A. Cullen JJ. Broadhurst KA. Are gastric, jejunal, or both forms of enteral feeding gastroprotective during stress? Journal of Surgical Research. 88(1):1-7, 2000 Jan.
  • J J Cullen, H S Park, J L Conklin, K S Ephgrave. Sphincter of Oddi motility may contribute to the jaundice of sepsis. Surg Forum, in press.
  • K S Ephgrave, D L Scott, A Ong, J J Cullen, K A Broadhurst. Are gastric, jejunal, or both forms of enteral feeding gastroprotective during stress? J of Surg Research, in press.
  • K S Ephgrave, C Buchmiller, M P Jones, J J Cullen. The Cup is Half Full: An analysis of clinical outcomes following feeding enterostomies. Am J Surg, in press.
  • D DuBay, K S Ephgrave, K Broadhurst, J Cullen. Intracerebroventricular calcitonin during stress prevents gastric hypercontractility and stress ulceration. Surgery, submitted.