The Sunrise Free Radical School is a feature of the annual meeting of the SFRBM. Below
are the slides for most of the lectures presented by the Faculty of the School since its inception in 1995.
________________________________________________________________________________________________________________
2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000
1999 | 1998 | 1997 | 1996 | 1995
Or view the Free Radical Workshop series presentations :
Thursday:
Garry Buettner, Ph.D., The University of Iowa
"What Are Free Radicals? " [PDF | Powerpoint]
Matthew Grisham, Ph.D., LSU Health Sciences Center
"Rates of Radical Production in Biological Tissues " [PDF | Powerpoint]Friday:
Jack Lancaster, Jr., Ph.D., The University of Alabama at Birmingham
"How Does Reaction vs. Diffusion Regulate ROS/RNS Biology " [PDF | Powerpoint]
Henry Forman, Ph.D., University of California, Merced
"Antioxidants" [PDF | Powerpoint]Saturday:
Paolo Di Mascio, Ph.D., University of São Paulo, Brazil
"How to Measure ROS and RNS in Biology " [PDF | Powerpoint]
Stanley Hazen, M.D., Ph.D., Cleveland Clinic Foundation
"Case Study- Impact of Free Radical Research on Disease: The Story of MPO " [PDF | Powerpoint]Sunday:
No Sunday School
2006 - Denver, Colorado
(November 15-19)
Thursday:
Arlan Richardson, Ph.D., The University of Texas Health Science Center -
"The Basics of Free Radical Chemistry and Their Biology." [PDF | Powerpoint]Friday:
Carol Cross, M.D., The University of California at Davis -
"Oxidative Stress at Respiratory Tract Surfaces: Focus Cystic Fibrosis." [PDF | Powerpoint]
Lin Mantell, M.D., Ph.D., The Feinstein Institute for Medical Research, New York -
"Oxygen, Redox Signaling and Lung Injury." [PDF | Powerpoint]Saturday:
Paul Brookes, Ph.D., University of Rochester -
"Mitochondria – More Than Just ATP Cows." [PDF | Powerpoint]
Alicia Kowaltowski, Ph.D., University of São Paulo -
"Mitochondrial ROS – Integrators of Protective and Pathologic Cell Signaling." [PDF]Sunday:
James Crapo, M.D., National Jewish Medical and Research Center -
"Redox, Kinetic, and Biological Necessities to Create an Effective Metalloenzyme-mimetic
in the Oxidative Stress Arena." [PDF | [Powerpoint]
2005 - Austin, Texas (November 16-20)Thursday:
Matthew Grisham, Ph.D., LSU Health Sciences Center -
"The Janus Face of Reactive Oxygen Species in Biology."
Frederick Domann, Ph.D., The University of Iowa -
"Biochemical Determinants Governing Redox Regulated Changes in Gene Expression and Chromatin Structure."
[PDF | Powerpoint]Friday:
Valerie O'Donnell, Ph.D., Cardiff University -
"Enzymatic Oxidation of Lipids: Mechanisms and Functions." [PDF | Powerpoint]
Jason D. Morrow, M.D., Vanderbuilt University -
"Detection of Lipid Peroxidation Products from Free Radical and Enzymatic Processes." [PDF | Powerpoint]Saturday:
James Friel, Ph.D., University of Manitoba -
"The Challenges of the Newborn." [PDF | Powerpoint]
Holly Van Remmen, Ph.D., University of Texas at San Antonio -
"Mitochondria, Antioxidants and Aging." [PDF | Powerpoint]Sunday:
Bruce Freeman, Ph.D., University of Alabama at Birmingham -
"Nitrated Fatty Acids: Formation and Actions." [PDF | Powerpoint]
2004 - St. Thomas, Virgin Islands (November 20-24)
Day One:
J. John Cohen, M.D., Ph.D., University of Colorado Medical School -
"Inflammation and Immunity from Innate Oysters to Adaptive Humans." [Powerpoint]Day Two:
Ned Porter, Ph.D., Vanderbuilt University -
"Mechanisms of Lipid Peroxidation."Day Three:
Henrik Poulsen, Ph.D., University Hospital Copenhagen -
"Oxidative DNA Modification and Cancer."Day Four:
Dean Jones, Ph.D., Emory University -
"Approaches to Define the Circuitry for Redox-Signaling Pathways."
2003 - Seattle, Washington (November 20-24)
Day One:
No lectures.Day Two:
Michael Davies, Ph.D., The Heart Research Institute -
"Protein Oxidations: Concepts, Mechanisms and New Insights." [PDF | Powerpoint]
Rodney Levine, M.D., Ph.D., F.O.S., National Institutes of Health -
"Protein Oxidation as a Marker of Oxidative Stress: Advantages and Disadvantages." [PDF]Day Three:
Gerald Pollack, Ph.D., University of Washington -
"Cells, Gels and Phase Transitions: The Working Principle of Life?" [PDF | Powerpoint]
Peter Wardman, Ph.D., Cancer Research UK -
"Lifetimes of Free Radicals and Excited States in Biology: When Fast Means Slow and Glowing Means Snuggling Up."
[PDF | Powerpoint]Day Four:
Valeria Culotta, Ph.D., Johns Hopkins University -
"SODs and Their Metallochaperones in Mitochondrial Antioxidant Defenses." [PDF | Powerpoint]
Garry R. Buettner, Ph.D., The University of Iowa -
"Chalcogen Chemistry and Biochemistry: The Many Faces of O, S, and Se in Proteins and Enzymes." [PDF | Powerpoint]
2002 - San Antonio, Texas (November 20-24)
Day One:
Periannan Kuppusamy, Ph. D., Davis Heart and Lung Institute -
"EPR Spying on Unpaired Electrons: What Information Can We Get?" [PDF | Powerpoint]
Bradley E. Britigan, M.D., University of Iowa Hospitals and Clinics -
"Iron: Mechanisms of Pro-Oxidant Behavior, Cellular Uptake and Organism Survival Skills." [PDF | Powerpoint]Day Two:
Jason D. Morrow, M.D., Vanderbuilt University -
"Looking for Lipid Peroxidation in Vitro and in Vivo: Is Seeing Believing?" [PDF | Powerpoint]
Simon Melov, Ph.D., The Buck Institute for Age Research -
"Oxidative Stress and Aging: Is Intervention Possible?" [PDF | Powerpoint]Day Three:
Garry R. Buettner, Ph.D., The University of Iowa -
"What is an Antioxidant? How do Antioxidants Work?" [PDF | Powerpoint]
Catherine Rice-Evans, Ph.D., King's College -
"Flavonoids and Polyphenols: What are they? What do they do? How do they do it?" [PDF | Powerpoint]Day Four:
Kenneth Hensley, Ph.D., Oklahoma Medical Research Foundation -
"Aging and Neurodegenerative Diseases: Models and Assessment of the Impact and Responses to ROS/RNS."
[PDF | Powerpoint]
James K. Hurst, Ph.D., Washington State University -
"What do *NO, O=NOO-, NO2, N2O2, N2O3, etc. do, and how do they do it: Basics." [PDF]
2001 - Research Triangle Park, North Carolina (November 11-15)
Day One:
Garry R. Buettner, Ph.D., The University of Iowa -
"Free Radical Basics: Concepts and Considerations." [PDF]
Tony Kettle, Ph.D., Christchurch School of Medicine -
"Heme-Peroxidase Biochemistry: Pulling Suprises From Their Pockets." [PDF]Day Two:
Judith Berliner, Ph.D., The University of California at Los Angeles -
"Molecular Regulation, by NO and Oxidized Lipids, of the Early Events of Atherosclerosis."
Mark Dewhirst, DVM, Ph.D., Duke University Medical Center -
"Oxygen - Levels, Distribution and Sensing in Tissues: What's Hip With HIF." [PDF]Day Three:
Sigmund Weitzman, M.D., Northwestern University -
"Chronic Inflammation and Cancer: Your Mother Was Right, Stop Picking at That."
Larry Marnett, Ph.D., Vanderbuilt University Medical Center -
"Oxyradicals, DNA Damage and Cancer: Molecular Changes and Their Mechanisms."Day Four:
Kelvin J.A. Davies, Ph.D., University of Southern California -
"The Spectrum of Responses of Oxidants in Proliferating Cells: Concentration, Concentration, Concentration."
[PDF]
Owen Griffith, Ph.D., Medical College of Wisconsin -
"Glutathione, The Ups and Downs of it's Manipulation - Consequences."
2000 - San Diego, California (November 16-20)
Day One:
Alberto Boveris, Ph.D., Universidad de Buenos Aires -
"Free Radical Generation by Mitochondria."
Bruce Kristal, Ph.D., Burke Medical Research Institute -
"Oxidative Damage and Antioxidant Defenses in Mitochondria." [PDFDay Two:
Martine Torres, Ph.D., University of Southern California -
"Cell Signaling Pathways or How to Get the Message Across."
Gary Schieven, Ph.D., Bristol-Myers Squibb Pharmaceutical Research Institute -
"Phosphatases: Regulators of Cell Signaling Systems." [PDF]Day Three:
Jack Lancaster, Ph.D., Louisiana State University Medical Center -
"The Physical Properties of Nitric Oxide: Critical Determinants of it's Biological Actions."
Tak Yee Aw, Ph.D., Louisiana State University medical Center -
"Molecular And Cellular Responses to Oxidative Stress and Changes in Oxidation-Reduction Imbalance."
[PDF | Powerpoint]Day Four:
Willem Koppenol, Ph.D., Swiss Federal Institute of Technology Zurich (ETHZ) -
"The Balance Between Oxidfative Stress and Antioxidants In Vivo - Science of Science Fiction?" [PDF]
John Erdman, Ph.D., University of Illinois at Urbana-Champaign -
"Dietary Reference Intake of Antioxidants - What Is The Science Behind The Closed Door?" [PDF]
1999 - New Orleans, Louisiana (November 18-22)
Day One:
Joseph S. Beckman, Ph.D., University of Alabama at Birmingham -
"ABC's of Reactive Nitrogen Species." [PDF]
Harry Ischiropolous, Ph.D., University of Pennsylvania -
"Biological Nitration: Mechanisms and Consequences." [Powerpoint]Day Two:
John P.Phillips, Ph.D., University of Guelph -
"Aging, CuZnSOD and Free Radicals."
Naomi Fukagawa, M.D., Ph.D., University of Vermont -
"Oxidative Stress inAging: Cause vs. Marker." [Powerpoint]Day Three:
Garry R. Buettner, Ph.D., The University of Iowa -
"Antioxidants: How They Work in Plastics and People." [PDF]
Larry W. Oberley, Ph.D., The University of Iowa -
"The Antioxidant Enzyme Network - A Symphony in Harmony." [PDF]Day Four:
Steve D. Aust, Ph.D., F.O.S. - Utah State University
"The Antioxidant Activity of Ferritin and Ceruloplasmin."
Shelly Lu, M.D., University of Southern California -
"Regulation of GSH Synthesis: A Key Antioxidant." [Powerpoint]
1998 - Washington D.C. (November 19-23)
Day One:
Nikki J. Holbrook, Ph.D., National Institutes of Health -
"Receptor Tyrosine Kinases/Mitogen Activated Kinases (MAPK)"
Yvonne Janssen-Heininger, Ph.D. - University of Vermont -
"Early Response Genes and Transcription Factors: AP-1 and NF-kB"Day Two:
Ann E. Aust, Ph.D., Utah State University -
"Oxidative Lessons." [PDF]
Bennett Van Houten, Ph.D., University of Texas Medical Branch -
"Damage and Repair of Mitochondrial DNA."Day Three:
Henry J. Forman, Ph.D., University of Southern California -
"Oxidative Signaling in Phagocytes." [Powerpoint]
Balaraman Kalyanaraman, Ph.D., The Medical College of Wisconsin -
"Cascades Generating ROS/RNS in Cells of the Immune System."Day Four:
Garry R. Buettner, Ph.D., The University of Iowa -
"Antioxidant Enzymes and Functions." [PDF]
Dean P. Jones, Ph.D., Emory University -
"What Does It Really Mean To Ask - What is the Redox State of a Cell, Tissue or Organism."
1997 - San Fransisco, California (November 19-22)
Day One:
Garry R. Buettner, Ph.D., The University of Iowa -
"Radicals and Radical Production: Tools of the Trade."
Freya Q. Schafer, Ph.D., The University of Iowa -
"Oxidative DNA Damage: A Radical Primer." [PDF]Day Two:
Balz Frei, Ph.D., Oregon State University -
"Vitamins C and E: Pro- and Antioxidant Effects."
Susan Thorpe, Ph.D., University of South Carolina -
"Glycoxidation: Chemistry and Role in LDL Oxidation."
Garry R. Buettner, Ph.D., The University of Iowa -
"How I write a Scientific Paper: Selling Your Data With Power Writing." [PDF]Day Three:
Charles (Skip) V. Smith, Ph.D., Baylor College of Medicine -
"Glutathione, The Great Protector: Quietly Doing All Things Everywhere...Almost."
Frederick (Rick) Domann, Ph.D., The University of Iowa -
"Redox Regulation of Gene Expression: The Alphabet Soup of Transcription Factors." [PDF]Day Four:
Maret G. Traber, Ph.D., University of California at Berkeley -
"The Biology of Vitamin E: The Hype Versus The Reality."
Stanton A. Glantz, Ph.D., University of California at San Fransisco -
"Second-Hand Smoke and The Ventilator Blues: A Significant Threat to Health?"
1996 - Miami Beach, Florida (November 21-25)
Day One:
Garry R. Buettner, Ph.D., The University of Iowa -
"Metals and Free Radicals: The Chemistry of Vitamin C."
James Dykens, Ph.D., Mitokor -
"Radical Production by Mitochondria: Function and Dysfunction."Day Two:
James Doroshow, Ph.D., City of Hope Medical Center -
"The Many and Varied GPx's."
Jay Heinecke, Ph.D., Washington University -
"Hemeperoxidases: Their Chemistry, Biology and Obstacles in Medicine."Day Three:
Joseph Beckman, Ph.D., University of Alabama at Birmingham -
"*NO and O=NOO- Basics."
L. Jackson Roberts, Ph.D., Vanderbuilt University -
"Detecting Lipid Peroxidation: The Latest and Greatest."Day Four:
Stetphen Hempel, Ph.D., University of Iowa Hospitals and Clinics -
"Fluorescence Detection of ROS."
Rafael Radi, Ph.D., University of the Republic -
"*NO, NOS, Cells - Pathology."
1995 - Pasadena, California (November 16-20)
Day One:
Garry R. Buettner, Ph.D., The University of Iowa -
"Basic Free Radical Chemistry: The Pecking Order and More."
Steven A. Aust, Ph.D., Utah State University -
"Metals, Free Radicals and Biological Rust."Day Two:
James Crapo, Ph.D., Duke University Medical Center -
"Cellular Production: The Ups and Downs."
Balaram Kalyanaraman, Ph.D., The Medical College of Wisconsin -
"Xenobiotics, Photoreaction, Nitric Oxide Donors: The Ins and Outs."Day Three:
Stuart M. Linn, Ph.D., University of California at Berkeley -
"Washing and Changing your Genes."
Balz Frei, Ph.D., Boston University Medical Center -
"Lipids and LDL: Rancidity and You."Day Four:
Norman I. Krinsky, Ph.D., Tufts University Medical Center -
"Low Molecular Weight Antioxidants: You Are What You Eat."
Larry W. Oberley, Ph.D., The University of Iowa -
"Your Antioxidant Enzyme Systems In Concert."
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