Link: University of Iowa
Roy J. and Lucille A. Carver College of Medicine

Michael Hoffman, MD, PhD


Medical School: University of Wisconsin School of Medicine and Public Health
Graduate School: University of Wisconsin-Madison, Department of Physiology
Residency/Fellowship: Internal Medicine, Physician Scientist Training Pathway, University of Iowa




Hoffman, M.S., Mitchell, G.S.  Spinal 5-HT7 Receptors and Protein Kinase A Constrain Intermittent Hypoxia-Induced Phrenic Long-term Facilitation.  J. Neuroscience (in review)

Hoffman, M.S.,Nichols, N., Macfarlane, P.M., and Mitchell, G.S. Phrenic Long Term Facilitation Following Acute Intermittent Hypoxia Requires Spinal ERK Activation but not TrkB Synthesis. J Appl Physiol, (in press)

Lovett-Barr, M.R., Satriotomo, I., Muir, G.D., Wilkerson, J.E., Hoffman, M.S., Vinit, S., Mitchell, G.S. Repetitive intermittent hypoxia induces respiratory and somatic motor recovery after chronic cervical spinal cord injury. J Neurosci

Hoffman, M.S., Mitchell, G.S. Spinal 5-HT7 receptor activation induces long-lasting phrenic motor facilitation. J Physiol

Hoffman, M.S., F. J. Golder, Mahamed, S., Mitchell, G. S., Spinal adenosine A2A receptor inhibition enhances phrenic long term facilitation following acute intermittent hypoxia." J Physiol,

Dale-Nagle, E. A., M. S. Hoffman, et al. Spinal plasticity following intermittent hypoxia: implications for spinal injury. Ann N Y Acad Sci 1198

Dale-Nagle, E. A., M. S. Hoffman, MacFarlane, P.M., Mitchell, G.S., Multiple pathways to long-lasting phrenic motor facilitation. Adv Exp Med Biol

Golder, F.J., Ranganathan, L., Satriotomo, I., Hoffman, M. S., Lovett-Barr, M.R., Watters, J.J., Baker-Herman, T.L., Mitchell, G. S., Spinal adenosine A2A receptor-activation elicits long-lasting phrenic motor facilitation. J. Neuroscience

Wilkerson, J.E.R., P.M. MacFarlane, M.S. Hoffman, and G.S. Mitchell. Respiratory plasticity elicited by intermittent hypoxia: roles of protein phosphatases and reactive oxygen species (review). Biochemical Society Transactions. Biochem Soc Trans

In preparation for submission

Wilkerson, J.E.R., Hoffman, M.S. and Mitchell, G.S. Hypoglossal Long-Term Facilitation is Elicited by Intermittent, but not Sustained Hypoxia

Guenther, C.H., Hoffman, M.S., Dale-Nagle, E.A., Mitchell, G.S., BDNF Protein Exhibits a Time of Day Change in the Hypoglossal, but not Phrenic, Motor Nucleus

Honors and Awards


University of Iowa
Roy J. and Lucille A. Carver College of Medicine
Physician Scientist Training Pathway
200 CMAB
Iowa City, IA 52242
(319) 335-6707