Iowa Integrated Screen

The Iowa Maternal Screening Program

• Information About
• Down Syndrome
• Trisomy 18
• Neural Tube Defects
• Iowa Integrated Screen
• Results from the Screen
• FAQ
• Summary

• Affiliated Agencies
• Iowa Department of Public Health
• University of Iowa Department OB/Gyn
• University of Iowa Hygienic Laboratory

Trisomy 18

Trisomy 18 is a chromosome abnormality caused by an extra chromosome number 18 in every cell of the body. Serious problems with growth and development are present before birth and physical problems such as an open spine or heart defect may be present. Many pregnancies with Trisomy 18 will miscarry and only 1 in 10 babies who are born with Trisomy 18 survive to one year of age, with most passing away soon after birth. Trisomy 18 is less common than Down syndrome; in an unscreened population, about 1 in every 6000 babies is born with Trisomy 18.

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