Molecular Genetic Pathology Fellowship Program
Description of Program: Our program builds on the internationally recognized leadership of the University of Iowa in the field of human genetics and a state of the art Molecular Diagnostics Laboratory to provide a unique training experience in all areas of molecular pathology. The Molecular Pathology Laboratory serves as the primary site for molecular testing of genetic, infectious and neoplastic diseases from the University of Iowa Hospitals and Clinics as well as for regional, national and international clients. We have over 30 diagnostic tests utilizing various methods including qualitative/quantitative PCR and real-time PCR, DNA sequencing, denaturing High Pressure Liquid Chromatography, traditional and capillary electrophoresis and Southern blotting. The MGP fellowship includes six months of hands-on training in the Molecular Pathology Laboratory divided into three blocks with special emphasis on molecular genetics, infectious disease and oncology, respectively. Another four months are spent predominantly in the Genetics Division of the Department of Pediatrics. This block includes two months of general genetics, a month of biochemical genetics and a month of cytogenetics training. The Cytogenetics Laboratory will provide exposure to traditional cytogenetics, FISH and Comparative Genomic Hybridization using microarray technology. During these rotations the fellow functions as a junior attending, with levels of responsibility and supervision appropriate for level of training and experience. The fellow is also exposed to administrative aspects of directing a modern molecular diagnostics laboratory.
The remaining two months are spent with independent test development in the Molecular Pathology Laboratory, or on basic research projects in any one of numerous laboratories associated with the program. The fellows are encouraged to use this time to obtain preliminary data serving as the basis for applications for career development grants from federal and private agencies.
Length of Program: 1 year. If there is mutual interest, further extension is possible in the form of postdoctoral training in one of the associated research laboratories.
Visas Accepted: Dependent on Individual Situation
Faculty/Key Staff:
| Molecular Pathology Laboratory: | |
| Nagy, Peter L. MD, PhD | Program Director, Molecular Oncology, Epigenetics |
| Bossler, Aaron, MD, PhD | Molecular Infectious Disease |
| Heusel, Jonathan, MD, PhD | Molecular Oncology and Infectious Disease |
| Moore, Steven, MD, PhD | Neuromuscular Disease |
| Division of Genetics: | |
| Berberich, Stan, PhD | Newborn Screening |
| Copeland, Sara, MD | Metabolic Genetics/Director |
| Matthews, Katherine, MD | Neuromuscular Clinic/Director |
| Murray, Jeffrey, MD | Craniofacial Clinic/Director |
| Patil, Shivanand, PhD | Cytogenetics/Director |
| Paulson, Henry, MD, PhD | Movement Disorders Clinic/Director |
| Sheffield, Val, MD, PhD | Molecular Genetics/Director |
| Smith, Richard, MD | Hearing Loss Clinic/Director |
| Stone, Edwin, MD, PhD | Eye Disease Clinic/Director |
| Willing, Marcia, MD, PhD | Connective Tissue Clinic/Director |
| Yankowitz, Jerome, MD | Prenatal Genetics/Director |
| Associated Research Laboratories: | |
| Campbell, Kevin, PhD | Neuromuscular Disorders |
| Cohen, Michael, MD | Pathogenesis of Prostate Cancer |
| Cook, Robert, MD, PhD | Effects of Alcohol on the Immune System |
| Di Paola, Jorge, MD | Genetics of Blood Clotting |
| Henry, Michael, PhD | Biology of Metastasis |
| Heusel, Jonathan, MD, PhD | NK cells in Infectious Disease and Cancer |
| Howe, James, MD | Pathogenesis of Colon Cancer Syndromes |
| Hsu, Mei-Yu, MD | Pathogenesis of Melanoma |
| Knudson, Michael, MD, PhD | Role of Bax in Apoptosis |
| Lentz, Steve, MD, PhD | Molecular Determinants of Blood Clotting |
| Mathews, Katherine, MD | Genetics of Neuromuscular Disorders |
| Murray, Jeffrey, MD | Genetics of Craniofacial Development |
| Nagy, Peter, MD, PhD | Epigenetic Regulation of Transcription |
| Paulson, Henry, MD, PhD | Inherited Neurodegenerative Disorders |
| O’Dorisio, Sue, MD, PhD | Biology of Neuroblastomas |
| Sheffield, Val, MD | Genetics of Obesity |
| Smith, Richard, MD | Genetics of Hearing Defects |
| Stone, Edwin, MD | Genetics of Eye Disease |
| Turek, Lubomir, MD | Pathogenesis of Cervical Carcinoma |
| Waldschmidt, Thomas, PhD | Immunology |
| Welsh, Michael, MD | Cystic Fibrosis Pathogenesis |
Requirements: MD and residency training in Pathology or Human Genetics
Stipend: Support is commensurate with the candidate's level of postgraduate training.
Applications: Inquiries should be addressed to: Peter L. Nagy, M.D., Ph.D., Program Director, The University of Iowa, Department of Pathology, 200 Hawkins Dr., Room C606 GH, Iowa City, IA 52242-1182. Email Address: peter-nagy@uiowa.edu
Phone: 319-353-4594 (voice) / 319-335-8453 (fax)