Hepatitis B Core Antibody, IgG & IgM
Label Mnemonic: | HBCB |
Epic code: | LAB622 |
Order form: | Laboratory Requisition |
Supply order: | Supply Order Form |
Billing: | Billing Policies |
CPT code: | 86704 |
Specimen(s):
Plasma
Collection Medium:
Plasma Separator Tube 4.5 mL |
Alternate
Collection Media:
Call laboratory for additional acceptable specimen collection containers.
Minimum:
5 mL whole blood from light green top tube or TWO light green top
microtubes for pediatric patients
Testing
Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around
Time:
1 hour (upon receipt in laboratory)
Reference Range:
Negative
Interpretive Data:
A negative result indicates that anti-HBc antibodies were not detected
in the sample. A positive result indicates presumptive evidence of
hepatitis B virus infection. Anti-HBc antibodies were detected in the
sample which suggests either on-going or previous HBV infection.
Comments:
Part of initial diagnostic hepatitis profile.
Current methods for the detection of anti-HBc antibodies may not detect all infected individuals. A negative test result does not exclude the possibility of exposure to or infection with HBV.
Assay updated with increased tolerance to biotin on 3/28/23.
Current methods for the detection of anti-HBc antibodies may not detect all infected individuals. A negative test result does not exclude the possibility of exposure to or infection with HBV.
Assay updated with increased tolerance to biotin on 3/28/23.
Test
Limitations:
The assay is unaffected by icterus < 25 mg/dL, hemolysis (Hb < 800
mg/dL), lipemia < 1000 mg/dL) and biotin is less than 1200 ng/mL..
Methodology:
Electrochemiluminescence Immunoassay
Sample
Processing:
Centrifuge at a speed and time necessary to get barrier separation of plasma/serum and cells within 1 hour of collection. Send specimen in original tube. Do Not transfer to another tube.
Each sample must be labeled with at least TWO full patient identifiers (First/Last Name & DOB are sufficient for non-UIHC affiliated clients) to avoid sample rejection/delays.
Each sample must be labeled with at least TWO full patient identifiers (First/Last Name & DOB are sufficient for non-UIHC affiliated clients) to avoid sample rejection/delays.
Sample
Storage:
Refrigerate.
All sample storage requirements are intended for delivery to UIHC within 24 hours of collection for testing. If samples won't arrive in this time period, please call the UIHC Core Lab for alternative storage/shipping instructions (319-356-3527).
All sample storage requirements are intended for delivery to UIHC within 24 hours of collection for testing. If samples won't arrive in this time period, please call the UIHC Core Lab for alternative storage/shipping instructions (319-356-3527).
Transport
Instructions:
Place labeled specimen into zip-lock type biohazard bag; seal bag.
Place completed requisition into outside pocket of bag.
Transport in cooler with refrigerated coolant packs.
Place completed requisition into outside pocket of bag.
Transport in cooler with refrigerated coolant packs.
CPT Code:
86704
See Additional Information:
Biotin Interference with Immunoassays
Biotin Interference with Immunoassays