A CBC must be ordered to perform a differential. Hematology instruments are automated differential screening instruments that identify WBC's by their size and staining activity. It performs a complete cell identification that includes neutrophils, lymphocytes, monocytes, basophils and eosinophils. The automated instruments count 32,000 white blood cells and statistically provide a more accurate differential count than a manual differential. All differentials will be analyzed on the instrument first. If the results fail the screening criteria, a manual differential will be performed. Pathologist approval is required to perform a manual differential on a specimen with an automated differential that passed the screening criteria. Cases with significant abnormal cells may require a differential with narrative description and interpretation by the pathologist. In these cases, results will be accompanied by the pathologist's report and charge. Please print, complete and submit the Advance Beneficiary Notice (ABN) along with the Laboratory Requisition before shipping the specimen.

Flow Cytometry Auto Diff Cytochemical Staining Manual Diff Wright's Stain