Carbamazepine
| Order Code: | CBZ |
| Order Form: | Laboratory Requisition |
Specimen:
Plasma
Collection Medium:
 |
| Plasma Separator Tube |
Alternate
Collection Media:
Call laboratory for additional acceptable specimen collection containers.
Minimum:
3 mL whole blood from light green top tube or 1 microtainer
Testing
Schedule:
24 hrs/day, 7 days a week, including holidays.
Analytic Time:
1 hour (upon receipt in laboratory)
Reference Range:
4-12 mcg/mL
Critical value: >12 mcg/mL
Comments:
Add-on testing permitted only within 24 hours of draw time. Unable to
add on requested testing if sample is greater than 24 hours old.
Test
Limitations:
Criterion: recovery plus or minus 0.5 ug/mL of initial value at
concentrations less than 5 ug/mL or plus or minus 10% of initial value
at concentrations greater than 5 ug/mL.
Icterus: No significant interference from bilirubin up to an I index of
60 (approximate bilirubin concentration: 60 mg/dL).
Hemolysis: No significant interference from hemoglobin up to an H index
of 1000 (approximate hemoglobin concentration: 1000 mg/dL).
Lipemia: No significant interference from triglycerides up to 1000
mg/dL.
No significant interference from total protein up to 12 g/dL or
rheumatoid factor up to 180 IU/mL.
The incidence of patients with antibodies to E. coli beta-galactosidase
is extremely low. However, some samples containing such antibodies can
result in artificially high carbamazepine results that do not fit the
clinical profile.
As with any assay employing mouse antibodies, the possibility exists
for interference by human anti-mouse antibodies (HAMA) in the sample,
which could cause falsely elevated results.
Methodology:
Enzymatic ImmunoAssay (EIA)
Sample
Processing:
Centrifuge at 3000 RPM for 10 minutes.
Aliquot plasma into labeled container and cap.
Aliquot plasma into labeled container and cap.
Sample
Storage:
Refrigerate.
Transport
Instructions:
Place specimen into zip-lock type bag, seal bag.
Place requisition into outside pocket of bag.
Transport in cooler with refrigerated coolant packs.
Place requisition into outside pocket of bag.
Transport in cooler with refrigerated coolant packs.
CPT Code:
80156
See Additional Information:
Chemistry Critical Lab Values
Chemistry Critical Lab Values