Myeloproliferative Neoplasia Panel

Label Mnemonic:	MPN, MPNBM
Epic code:	LAB8429 for Blood LAB8430 for Bone Marrow
Order form:	Comprehensive Hematopathology Requisition
Supply order:	Supply Order Form
Billing:	Billing Policies
CPT code:	81219, 81270, 81403, 81403

Specimen(s):

Whole Blood or Bone Marrow Aspirate

Collection Medium:

Pink top tube 6 mL (K2-EDTA)

Minimum:

5 mL whole blood or 3 mL bone marrow aspirate in pink top tube (EDTA). Testing requires a dedicated collection tube.

Testing Schedule:

Weekly

Turn Around Time:

7-10 days

Comments:

This test includes the following FOUR tests:
Calreticulin Mutation Analysis with Interpretation
JAK2 Common Mutation V617F Analysis with Interpretation
MPL codon 515 Mutation
JAK2 Exon 12 Mutation

Methodology:

Polymerase Chain Reaction (PCR) fragment analysis and next generation sequencing

Instructions:

Testing requires a dedicated tube.

Sample Processing:

Label transport tube with two patient identifiers, date and time of collection.
Patient's age and sex is required on requisition for processing.
Relevant clinical information must be submitted with specimen in order to provide correct interpretation of test results.
Do Not Centrifuge.

Sample Storage:

Room temperature for up to 24 hours, then refrigerate the whole blood if it is necessary to be held overnight, weekends, or holidays.

Transport Instructions:

Place requisition into outside pocket of bag.
Recommend early AM overnight shipping or equivalent if not on courier service.
Ship refrigerated.

CPT Code:

81219, 81270, 81403, 81403