C3 Complement Component, Plasma

C3 Complement Component

Order Code:	C3
Order Form:	Laboratory Requisition

Specimen:

Plasma

Collection Medium:

Plasma Separator Tube

Alternate Collection Media:

Call laboratory for additional acceptable specimen collection containers.

Minimum:

3 mL whole blood from light green top tube or 1 microtainer

Testing Schedule:

24 hrs/day, 7 days a week, including holidays.

Analytic Time:

1 hour (upon receipt in laboratory)

Reference Range:

90-180 mg/dL

Comments:

Measures concentration by specific antibody. If cryoglobulin present or suspected, collect specimen as directed for 'Cryoglobulin, Serum'.

Test Limitations:

Criterion: Recovery within plus or minus 10% of initial value. Icterus: No significant interference up to an I index of 60 (approximate conjugated and unconjugated bilirubin concentration: 60 mg/dl or 1026 umol/l). Hemolysis: No significant interference up to an H index of 1000 (approximate hemoglobin concentration: 1000 mg/dl or 621 umol/l) Lipemia (Intralipid): No significant interference up to an L index of 1000 (approximate triglycerides concentration: 2000 mg/dl or 22.8 mmol/l). There is poor correlation between turbidity and triglycerides concentration. Rheumatoid factors up to 1200 IU/ml do not interfere. No high-dose hook effect is seen up to a C3c concentration of 1250 mg/dl. Monoclonal gammopathy sera of the IgA or IgM type can interfere with the C3c determination.

Methodology:

Immunoturbimetric

Sample Processing:

Centrifuge at 3000 RPM for 10 minutes.
Specimen must be in plastic vial.
Label transport tube with two patient identifiers, date and time of collection.

Sample Storage:

Refrigerate up to 8 days or freeze.

Transport Instructions:

Place specimen into zip-lock type bag, seal bag.
Place requisition into outside pocket of bag.
Place dry ice on top of specimen in styrofoam container.

CPT Code:

86160