Acetaminophen
| Label Mnemonic: | APAP |
| Epic code: | LAB43 |
| Order form: | Laboratory Requisition |
| Supply order: | Supply Order Form |
| Billing: | Billing Policies |
| CPT code: | 80329 |
Specimen(s):
Plasma
Collection Medium:
 |
| Plasma Separator Tube 4.5 mL |
Alternate
Collection Media:
Call laboratory for additional acceptable specimen collection containers.
Minimum:
3 mL; light green top tube or ONE Microtainer®.
Testing
Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around
Time:
1 hour (upon receipt in laboratory)
Reference Range:
Acetaminophen concentrations greater than 150 μg/mL at four hours after ingestion or greater than 40 μg/mL at 12 hours after ingestion are often associated with toxicity. Critical value: >40 μg/mL
Test
Limitations:
Hemolysis: No significant interference up to an H index of 800
(approximate hemoglobin concentration: 800 mg/dL).
Lipemia: No significant interference up to an L index of 400 (approximate triglycerides concentration: 800 mg/dL). Note there is poor correlation between turbidity and triglyceride concentration.
Icterus: Icterus can cause positive interference with the acetaminophen assay. Testing is cancelled with an icteric index of 30 or greater.
Lipemia: No significant interference up to an L index of 400 (approximate triglycerides concentration: 800 mg/dL). Note there is poor correlation between turbidity and triglyceride concentration.
Icterus: Icterus can cause positive interference with the acetaminophen assay. Testing is cancelled with an icteric index of 30 or greater.
Methodology:
Spectrophotometric
Sample
Processing:
Centrifuge at a speed and time necessary to get barrier separation of plasma/serum and cells within 1 hour of collection. Send specimen in original tube. Do Not transfer to another tube.
Each sample must be labeled with at least TWO full patient identifiers (First/Last Name & DOB are sufficient for non-UIHC affiliated clients) to avoid sample rejection/delays.
Each sample must be labeled with at least TWO full patient identifiers (First/Last Name & DOB are sufficient for non-UIHC affiliated clients) to avoid sample rejection/delays.
Sample
Storage:
Refrigerate.
All sample storage requirements are intended for delivery to UIHC within 24 hours of collection for testing. If samples won't arrive in this time period, please call the UIHC Core Lab for alternative storage/shipping instructions (319-356-3527).
All sample storage requirements are intended for delivery to UIHC within 24 hours of collection for testing. If samples won't arrive in this time period, please call the UIHC Core Lab for alternative storage/shipping instructions (319-356-3527).
Transport
Instructions:
Place labeled specimen into zip-lock type biohazard bag; seal bag.
Place completed requisition into outside pocket of bag.
Transport in cooler with refrigerated coolant packs.
Place completed requisition into outside pocket of bag.
Transport in cooler with refrigerated coolant packs.
CPT Code:
80329
See Additional Information:
Chemistry Critical Lab Values
Chemistry Critical Lab Values