Toxoplasmosis Antibody, IgG
| Order Code: | TOXOG |
| Order Form: | Laboratory Requisition |
Specimen:
Serum
Collection Medium:
 |
| Red top tube |
Minimum:
Preferred Minimum: 1 mL serum
Absolute Minimum: 0.5 mL serum
Absolute Minimum: 0.5 mL serum
Rejection Criteria:
Contaminated, grossly hemolyzed or heat-inactivated specimens.
Analytic Time:
24 hours upon receipt at reference laboratory
Reference Range:
6 IU/mL or less: Negative - No clinically significant level of
Toxoplasma gondii IgG antibody detected.
7-8 IU/mL: Equivocal - Repeat testing in 10-14 days may be helpful.
9 IU/mL or greater: Positive - Significant level of Toxoplasma gondii IgG antibody detected, which may indicate current or past infection.
7-8 IU/mL: Equivocal - Repeat testing in 10-14 days may be helpful.
9 IU/mL or greater: Positive - Significant level of Toxoplasma gondii IgG antibody detected, which may indicate current or past infection.
Interpretive Data:
The best evidence for current infection is a significant change on two
appropriately timed specimens, where both tests are done in the same
laboratory at the same time.
Comments:
Acute and convalescent specimens must be labeled as such; parallel
testing is preferred and convalescent specimens must be received within
30 days from receipt of the acute specimens. Please mark specimen
plainly as "acute" or "convalescent."
Test
Limitations:
Positive results for the IgM assay are presumptive. Further testing
must be performed to determine the presence or absence of IgM
antibodies.
Negative test results may occur early in the course of infection.
During reactivation, an IgM response may not occur, or be present at
levels to low to be detected.
Positive results from cord blood are usually the result of passive
transfer of antibodies from the mother to the fetus.
Interpret positive results with caution if patients have received blood
products within the past three months.
In an immunocompromised patient, a negative result may not rule out
infection, because of a diminished immune response.
Methodology:
Chemiluminescent Immunoassay
Sample
Processing:
Aliquot serum into labeled container and cap.
Centrifuge at 3000 RPM for 10 minutes.
Centrifuge within one hour of draw time.
Label transport tube with two patient identifiers, date and time of collection.
Centrifuge at 3000 RPM for 10 minutes.
Centrifuge within one hour of draw time.
Label transport tube with two patient identifiers, date and time of collection.
Sample
Storage:
Refrigerate serum 2-8°C.
Transport
Instructions:
Place specimen into zip-lock type bag, seal bag.
Use refrigerated coolant packs.
Place requisition into outside pocket of bag.
Use refrigerated coolant packs.
Place requisition into outside pocket of bag.
CPT Code:
86317
See also:
Toxoplasmosis Antibody, IgM, Serum
Toxoplasmosis Antibody, IgM, Serum