Uric Acid
| Order Code: | URIC |
| Order Form: | Laboratory Requisition |
Specimen:
Plasma
Collection Medium:
 |
| Plasma Separator Tube |
Alternate
Collection Media:
Call laboratory for additional acceptable specimen collection containers.
Minimum:
3 mL whole blood in light green top tube or ONE microtainer for
pediatric patients.
Testing
Schedule:
24 hrs/day, 7 days a week, including holidays.
Analytic Time:
1 hour (upon receipt in laboratory)
Reference Range:
Confirm 3.4-7.0 mg/dL (males) and 2.4-5.7 mg/dL (females)
Pediatric Reference Ranges:
Age Range Units
0-2 years 2.0-7.0 mg/dL
2-12 years 2.0-6.5 mg/dL
12-14 years 2.0-7.0 mg/dL
Test
Limitations:
Criterion: Recovery within plus or minus 10% of initial values
Plasma
Icterus: No significant interference up to an I index of 40
(approximate conjugated and unconjugated bilirubin concentration 40
mg/dL or 684 umol/l).
Hemolysis: No significant interference up to an H index of 1000
(approximate hemoglobin concentration: 1000 mg/dL or 621 umol/l).
Lipemia (Intralipid): No significant interference up to an L index of
1000 (approximate triglycerides concentration: 2000 mg/dL or 22.8
mmol/l).
There is poor correlation between turbidity and triglycerides
concentration.
Ascorbic acid less than 30 mg/dL does not interfere.
Of the drugs tested in vitro, o-methyldopa, desferoxamine and calcium
dobesilate (e.g. Dexium) cause interference at therapeutic
concentrations (uric acid level artificially low).
Uricase reacts specifically with uric acid. Other purine derivatives
can inhibit the uric acid reaction.
Reference:
Glick MR, Ryder KW, Jackson SA. Graphical Comparisons of Interferences
in Clinical Chemistry Instrumentation. Clin Chem 1986;32:470-474.
Methodology:
Enzymatic
Sample
Processing:
Centrifuge at 3000 RPM for 10 minutes.
Aliquot plasma into labeled container and cap.
Aliquot plasma into labeled container and cap.
Sample
Storage:
Room temperature or refrigerate if stored overnight.
Transport
Instructions:
Place specimen into zip-lock type bag, seal bag.
Place requisition into outside pocket of bag.
Ship ambient or refrigerate.
Place requisition into outside pocket of bag.
Ship ambient or refrigerate.
CPT Code:
84550
See also:
Uric Acid-Other, Body Fluid (e.g., surgical drain, pericardial, peritoneal, peritoneal dialysis, pleural, or synovial)
Uric Acid-Other, Body Fluid (e.g., surgical drain, pericardial, peritoneal, peritoneal dialysis, pleural, or synovial)