Measles (Rubeola ) Antibody, IgG
Order Code: MEASL
Order Form: Laboratory Requisition
Specimen(s):
Plasma
Collection Medium:
Plasma Separator Tube
Alternate Collection Media:
Call laboratory for additional acceptable specimen collection containers.
Minimum:
3.0 mL whole blood from light green top tube or TWO microtainers.
Testing Schedule:
24 hrs/day, 7 days a week, including holidays.
Turn Around Time:
3 hours (upon receipt in laboratory)
Reference Range:
Reference range and methodology changed effective 12/11/2012.

0.8 AI or less: Negative - No significant level of detectable measles (rubeola) IgG antibody.

0.9-1.0 AI: Equivocal - Repeat testing in 10-14 days may be helpful.

1.1 AI or greater: Positive - IgG antibody to measles (rubeola) detected, which may indicate a current or past exposure/immunization to measles (rubeola).
Interpretive Data:
The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.

Measles IgG antibody can be formed following measles infection or after measles vaccination. A reactive result is consistent with immune status to measles virus. Non-reactive and equivocal results flag as abnormal in Epic which indicates non-immune or equivocal immune status to measles. A non-reactive result does NOT imply measles infection. If ordered in workup of possible measles infection, the IgG antibody results should be interpreted in conjunction with other laboratory tests, clinical history, and physical examination.
Comments:
Indicate whether specimen is "ACUTE", "CONVALESCENT" or "RANDOM." RANDOM would be appropriate selection if the test is ordered to determine patient immunity status for measles (e.g., for student or employee health).

For workup related to possible measles infection, acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "ACUTE" or "CONVALESCENT."
Methodology:
Multiplex Flow Immunoassay
Sample Processing:
Centrifuge at 3000 RPM for 10 minutes.
Aliquot plasma into labeled container and cap.
Sample Storage:
Refrigerate.
Transport Instructions:
Place specimen into zip-lock type bag, seal bag.
Place requisition into outside pocket of bag.
Transport in cooler with refrigerated coolant packs.
CPT Code:
86765